cross-reaction


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cross-reaction

 [kros´re-ak-shun]
an interaction between an antibody and an antigen closely related to the antigen that specifically stimulated synthesis of the antibody.

cross-re·ac·tion

antibodies evoked by antigens with shared or similar idiotypic determinants may bind or cross-react with each other's respective antigens, even if their antigen-specificity is not identical.

cross-reaction

(krôs′rē-ăk′shən, krŏs′-)
n.
The reaction between an antigen and an antibody that was generated against a different but similar antigen.

cross′-re·act′ v.
cross′-re·ac′tive adj.
cross′-re·ac·tiv′i·ty n.

cross-reaction

Immunology A partial reaction or 'recognition' of an epitope by an antibody generated in response to another antigen

cross-re·ac·tion

(kraws'rē-ak'shŭn)
A specific reaction between an antiserum and an antigen complex other than the antigen complex that evoked the various specific antibodies of the antiserum. It is due to at least one antigenic determinant that is included among the determinants of the other complex.

cross-reaction

The association of an ANTIBODY with an ANTIGEN that differs from the antigen that first stimulated the production of the antibody. Cross reaction is unlikely unless there is close chemical similarity between the two antigens. Some diseases are believed to result because of antigenic similarities between certain body tissues and parts of infecting organisms, such as STREPTOCOCCI.

Cross-reaction

A reaction that occurs in blood testing when a disease agent reacts to the specific antibody for another disease agent. Cross-reactions are common in blood tests for fluke infections because the different species are closely related.
References in periodicals archive ?
Due to the possibility of cross-reaction with piperacillin-tazobactam in the Platelia Aspergillus EIA test some authors have suggested that testing of suspected antibiotic batches remains the only indicator of possible false EIA positivity [5].
The B6-30N antibody also cross-reacts with a substance located within the optic cups of light-adapted animals, but the cross-reaction is considerably weaker.
(L.) amazonensis antigen was used, cross-reactions with other pathologies were frequent, mainly with Chagas disease and paracoccidioidomycosis.
Cross-reaction with luteinizing hormone R-core is responsible for the age-dependant increase of immunoreactive /3-core fragment of human chorionic gonadotropin in women with nonmalignant conditions.
Purified [beta]-LH-core did not cross-react in the free hCG[beta], free [alpha]-subunit, and intact hCG assays, but showed 100% cross-reaction in the LH and S-504 [beta]-core assays.
SFGR/TGR cross-reactions and apparent co-infections could also impair clinical differentiation of specific rickettsioses.
In this case, the bias caused by the pronounced cross-reaction of the acylglucuronide in the immunoassay apparently did not compromise the predictive power of the test.
No cross-reaction occurs in patients with Chagas disease, but some cross-reactions are found in patients with glandular tuberculosis or lepromatous leprosy (4).
Scarpinato recommends against use of a cephalosporin because of the 6% risk that the patient will have a cross-reaction to it.
Reports quoting risks on the lower end are based upon laboratory testing for maternal IgM antibodies, which couldn't rule out cross-reaction with other flaviviruses, including dengue virus, which is common in most of the same locales as Zika.
To further confirm the absence of any cross-reaction, experiments were individually performed in the presence of the reagents except for GoTaq DNA polymerase or Afu flap endonuclease or both.
Cross-reaction of antisera with hemocytes of four crabs by FCM.