cross-reaction

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Related to cross-react: cross-reactivity

cross-reaction

 [kros´re-ak-shun]
an interaction between an antibody and an antigen closely related to the antigen that specifically stimulated synthesis of the antibody.

cross-re·ac·tion

antibodies evoked by antigens with shared or similar idiotypic determinants may bind or cross-react with each other's respective antigens, even if their antigen-specificity is not identical.

cross-reaction

(krôs′rē-ăk′shən, krŏs′-)
n.
The reaction between an antigen and an antibody that was generated against a different but similar antigen.
cross′-re·act′ v.
cross′-re·ac′tive adj.
cross′-re·ac·tiv′i·ty n.

cross-reaction

Immunology A partial reaction or 'recognition' of an epitope by an antibody generated in response to another antigen

cross-re·ac·tion

(kraws'rē-ak'shŭn)
A specific reaction between an antiserum and an antigen complex other than the antigen complex that evoked the various specific antibodies of the antiserum. It is due to at least one antigenic determinant that is included among the determinants of the other complex.

cross-reaction

The association of an ANTIBODY with an ANTIGEN that differs from the antigen that first stimulated the production of the antibody. Cross reaction is unlikely unless there is close chemical similarity between the two antigens. Some diseases are believed to result because of antigenic similarities between certain body tissues and parts of infecting organisms, such as STREPTOCOCCI.

Cross-reaction

A reaction that occurs in blood testing when a disease agent reacts to the specific antibody for another disease agent. Cross-reactions are common in blood tests for fluke infections because the different species are closely related.
Mentioned in: Fluke Infections, Tuberculin Skin Test
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References in periodicals archive ?
However, all current clinically approved BNP and NT-proBNP assays cross-react with proBNP, and all documented BNP assays also measure BNP metabolites to varying degrees (20, 30).
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The focus of our laboratory research was to identify food proteins that have the potential to cross-react with pancreatic islet cells by evaluating immune reactivity between antibodies made against target tissue antigens involved in diabetes and various dietary proteins.
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The test resulted positively for our patient, who also had an immune disorder, producing antibodies which cross-reacted with the hantavirus recombinant antigen.
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Cross-reactivity of outer membrane proteins of Campylobacter species with cholera toxin
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Drug toxicology screens do not specifically test for dextromethorphan, but the drug can cross-react with the test for phencyclidine (PCP).
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Research is underway to assure no other bacteria cross-react with the magnetic beads.
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As a result, persons sensitive to poison ivy will often cross-react to ginkgo products.
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Concerns that the antibody response to beta-hCG may have the potential to cross-react with and interrupt other hormones produced in the pituitary gland have slowed the progress of anti-hCG clinical research.
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Johnson's argument boils down to two key points: 1) HIV has never been properly isolated, so the HIV proteins used in the tests haven't been proven to actually come from HIV, 2) Even if HIV is real, the proteins are not unique and cross-react with many other antigens, rendering a positive result meaningless.
HIV Testing 101 (Part 2 of 2)

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