cross-reaction

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Related to cross-react: cross-reactivity

cross-reaction

 [kros´re-ak-shun]
an interaction between an antibody and an antigen closely related to the antigen that specifically stimulated synthesis of the antibody.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

cross-re·ac·tion

antibodies evoked by antigens with shared or similar idiotypic determinants may bind or cross-react with each other's respective antigens, even if their antigen-specificity is not identical.
Farlex Partner Medical Dictionary © Farlex 2012

cross-reaction

(krôs′rē-ăk′shən, krŏs′-)
n.
The reaction between an antigen and an antibody that was generated against a different but similar antigen.
cross′-re·act′ v.
cross′-re·ac′tive adj.
cross′-re·ac·tiv′i·ty n.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

cross-reaction

Immunology A partial reaction or 'recognition' of an epitope by an antibody generated in response to another antigen
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

cross-re·ac·tion

(kraws'rē-ak'shŭn)
A specific reaction between an antiserum and an antigen complex other than the antigen complex that evoked the various specific antibodies of the antiserum. It is due to at least one antigenic determinant that is included among the determinants of the other complex.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

cross-reaction

The association of an ANTIBODY with an ANTIGEN that differs from the antigen that first stimulated the production of the antibody. Cross reaction is unlikely unless there is close chemical similarity between the two antigens. Some diseases are believed to result because of antigenic similarities between certain body tissues and parts of infecting organisms, such as STREPTOCOCCI.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

Cross-reaction

A reaction that occurs in blood testing when a disease agent reacts to the specific antibody for another disease agent. Cross-reactions are common in blood tests for fluke infections because the different species are closely related.
Mentioned in: Fluke Infections, Tuberculin Skin Test
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.
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References in periodicals archive ?
However, all current clinically approved BNP and NT-proBNP assays cross-react with proBNP, and all documented BNP assays also measure BNP metabolites to varying degrees (20, 30).
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The focus of our laboratory research was to identify food proteins that have the potential to cross-react with pancreatic islet cells by evaluating immune reactivity between antibodies made against target tissue antigens involved in diabetes and various dietary proteins.
Detection of Islet Cell Immune Reactivity with Low Glycemic Index Foods: Is This a Concern for Type 1 Diabetes?
The test resulted positively for our patient, who also had an immune disorder, producing antibodies which cross-reacted with the hantavirus recombinant antigen.
Microscopic polyangiitis with positive Hantaan virus-specific immunoglobuline m antibody caused by cross reaction: a case report
Major outer membrane proteins from many Campylobacter species cross-react with cholera toxin.
Cross-reactivity of outer membrane proteins of Campylobacter species with cholera toxin
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Drug toxicology screens do not specifically test for dextromethorphan, but the drug can cross-react with the test for phencyclidine (PCP).
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Research is underway to assure no other bacteria cross-react with the magnetic beads.
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As a result, persons sensitive to poison ivy will often cross-react to ginkgo products.
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Concerns that the antibody response to beta-hCG may have the potential to cross-react with and interrupt other hormones produced in the pituitary gland have slowed the progress of anti-hCG clinical research.
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Investigations are under way to make sure that no other bacteria cross-react with the magnetic beads.
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Johnson's argument boils down to two key points: 1) HIV has never been properly isolated, so the HIV proteins used in the tests haven't been proven to actually come from HIV, 2) Even if HIV is real, the proteins are not unique and cross-react with many other antigens, rendering a positive result meaningless.
HIV Testing 101 (Part 2 of 2)

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