cross resistance


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cross resistance

The ability of bacteria, viruses, or cancer cells to live and reproduce despite treatment with more than one drug. In cancer therapy, resistance to a wide range of unrelated drugs may occur after resistance to a single agent has developed.
Synonym: multidrug resistance; multiple drug resistance See: gene amplification
See also: resistance
References in periodicals archive ?
The drug shows little cross resistance with other antibiotics because it's structurally unique and targets an early stage in bacterial protein synthesis.
aureus strains develop a resistance against commonly used antibiotics, agar diffusion tests were carried out to check for cross resistance.
Key words: Pectinophora gossypiella, spinosad, enzyme detoxification, cross resistance, resistance ratio.
In Belgium, Van Leeuwen et al., [19] reported that bifenazate-resistant strain lacked cross resistance to many different chemical classes and modes of action of other acaricides.
To date active ingredient has not been reported to show cross resistance with any insecticide for which resistant mite or whitefly field populations have been identified (Palumbo 2004).
In early stage studies, GSK '052 has shown robust activity against multi-resistant gram-negative bacteria with no cross resistance to existing classes of antibiotics.