cromolyn


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Related to cromolyn: cromolyn sodium

cromolyn

 [kro´mŏ-lin]
a drug that inhibits the release of chemical mediators of immediate sensitivity from basophils and mast cells, administered by inhalation or intranasally for prophylaxis and treatment of bronchial asthma and allergic rhinitis, orally for treatment of mastocytosis, and topically to the conjunctiva for prevention and treatment of allergen-induced inflammation of the conjunctiva or cornea. It has the advantage of reducing or eliminating the need for steroids and sympathomimetics. Used in the form of its disodium salt, cromolyn sodium.

cromolyn

(krō′mə-lĭn)
n.
A drug, C23H16O11, given in the form of its sodium salt, that inhibits the release of histamine from mast cells and is used as an inhalant or topically in the treatment of allergies and to prevent asthmatic attacks.
References in periodicals archive ?
Rats treated with the MC stabilizer Cromolyn showed less severe cognitive deficits after surgery, accompanied by increased BBB stability [16] and reduced microglia and astrocyte activation [79, 80].
In our case, the eye symptoms increased especially with the flare up of skin lesions possibly due to histamine release into the mucous membrane.5 Complete clearance after treatment with topical antihistamines and mast cell stabilizer (cromolyn sodium) point to a role for histamine and elevated total serum tryptase level.
The need for multiple daily doses, the intranasal application and the time needed for effect limit the use of cromolyn sodium.
Cromolyn Sodium for Insulin-Induced Lipoatrophy: Old Drug, New Use.
Cromolyn prevents the extrusion of granules containing the mediators of inflammation.
Dr Wasim Khawaja said people with seasonal allergies, who could not avoid pollen, the symptoms could be controlled with medication on advice of physicians, including antihistamines, corticosteroids, and cromolyn sodium, any of which could be used alone or in combination.
Successful treatment with other anti-inflammatory medications, such as leukotriene modifiers (montelukast) and mast cell stabilizers (cromolyn), anti-allergic drugs (budesonide) has been reported.
Mast cell stabilizing therapy with topical 4% sodium cromolyn has been reported to reverse early and prevent new lipoatrophic lesions (3).
nasal sprays containing cromolyn sodium, and eye drops.
"Treatment of ragweed allergic conjunctivitis with 2% cromolyn solution in unit doses," Ann.
Medications used to treat EE include topical glucocorticoids, cromolyn sodium (which blocks allergic reactions to foods), and leukotriene receptor antagonists.
These include hyperalimentation, corticosteroids, H2-receptor antagonists, antibiotics, acid suppression, Cromolyn Sodium, anabolic steroids, surgery, and combinations of these therapies (7).