Rats treated with the MC stabilizer Cromolyn
showed less severe cognitive deficits after surgery, accompanied by increased BBB stability  and reduced microglia and astrocyte activation [79, 80].
In our case, the eye symptoms increased especially with the flare up of skin lesions possibly due to histamine release into the mucous membrane.5 Complete clearance after treatment with topical antihistamines and mast cell stabilizer (cromolyn
sodium) point to a role for histamine and elevated total serum tryptase level.
The need for multiple daily doses, the intranasal application and the time needed for effect limit the use of cromolyn
Sodium for Insulin-Induced Lipoatrophy: Old Drug, New Use.
prevents the extrusion of granules containing the mediators of inflammation.
Dr Wasim Khawaja said people with seasonal allergies, who could not avoid pollen, the symptoms could be controlled with medication on advice of physicians, including antihistamines, corticosteroids, and cromolyn
sodium, any of which could be used alone or in combination.
Successful treatment with other anti-inflammatory medications, such as leukotriene modifiers (montelukast) and mast cell stabilizers (cromolyn
), anti-allergic drugs (budesonide) has been reported.
Mast cell stabilizing therapy with topical 4% sodium cromolyn
has been reported to reverse early and prevent new lipoatrophic lesions (3).
nasal sprays containing cromolyn
sodium, and eye drops.
"Treatment of ragweed allergic conjunctivitis with 2% cromolyn
solution in unit doses," Ann.
Medications used to treat EE include topical glucocorticoids, cromolyn
sodium (which blocks allergic reactions to foods), and leukotriene receptor antagonists.
These include hyperalimentation, corticosteroids, H2-receptor antagonists, antibiotics, acid suppression, Cromolyn
Sodium, anabolic steroids, surgery, and combinations of these therapies (7).