cromolyn


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Related to cromolyn: cromolyn sodium

cromolyn

 [kro´mŏ-lin]
a drug that inhibits the release of chemical mediators of immediate sensitivity from basophils and mast cells, administered by inhalation or intranasally for prophylaxis and treatment of bronchial asthma and allergic rhinitis, orally for treatment of mastocytosis, and topically to the conjunctiva for prevention and treatment of allergen-induced inflammation of the conjunctiva or cornea. It has the advantage of reducing or eliminating the need for steroids and sympathomimetics. Used in the form of its disodium salt, cromolyn sodium.

cromolyn

/cro·mo·lyn/ (kro´mol-in) an inhibitor of the release of histamine and other mediators of immediate hypersensitivity from mast cells; used as the sodium salt for prophylaxis and treatment of allergic rhinitis, bronchial asthma associated with allergy, and allergen-induced inflammation of the conjunctiva or cornea, and for treatment of mastocytosis.

cromolyn

(krō′mə-lĭn)
n.
A drug, C23H16O11, given in the form of its sodium salt, that inhibits the release of histamine from mast cells and is used as an inhalant or topically in the treatment of allergies and to prevent asthmatic attacks.

cromolyn

a mast cell stabilizer which, if administered prior to exposure to allergens, prevents degranulation and release of histamine in a hypersensitivity reaction. Administered as an aerosol for prophylaxis of bronchial asthma and allergic rhinitis. Investigated for use in the treatment of chronic obstructive pulmonary disease in horses. Called also cromoglycate.
References in periodicals archive ?
05% betamethasone dipropionate cream, and oral cromolyn sodium 100 mg qid for our patient, but this failed to significantly improve the macules.
The need for multiple daily doses, the intranasal application and the time needed for effect limit the use of cromolyn sodium.
Cromolyn Sodium for Insulin-Induced Lipoatrophy: Old Drug, New Use.
Cromolyn prevents the extrusion of granules containing the mediators of inflammation.
c) Be treated with 2% or 4% sodium cromolyn and maintain contact lens wear
I have had only one cataract in a child on cromolyn (and we do not think it was from inhaled steroids), and so far I have had no deaths among my asthmatic patients.
Then they gave some of the mice two antihistamines, one called ketotifen fumarate, sold by Novartis AG under the brand name Zaditor and generically available cromolyn.
For further analysis, Shi and colleagues took a group of obese and diabetic mice and, for a period of two months, treated them with over-the-counter allergy drugs ketotifen fumarate (also called Zaditor) or cromolyn.
Cromolyn sodium is most useful in controlling gastrointestinal effects of systemic mastocytosis and administration in the perioperative period is not critical (34).
Effects of quercetin (10 mg/mL, inhalation for 2 min) compared with cromolyn sodium, salbutamol, and dexamethasone inhalations, respectively.
Cromolyn sodium (Nasalcrom) is a nasal spray that in some people helps to prevent allergic reactions from starting.
Conventional antiasthmatic compounds, such as sodium cromolyn and sodium cromoglycate, were developed from analogs of the naturally occurring furanochromone khellin (visammin), found in the Asian plant Ammi visnaga.