cribriform carcinoma


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cribriform carcinoma

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41,42) Neither invasive tubular carcinoma nor invasive cribriform carcinoma expresses conventional myoepithelial markers, (12,35,59) and nests of cribriform DCIS display an outer rim of MECs.
Gleason Grading of Cribriform Carcinomas Gleason Histologic Pattern Grade 1) Rounded, well-circumscribed cribriform glands of the same size as normal glands (resembling cribriform high-grade PIN) 3 2) Large cribriform glands 4 3) Cribriform glands with irregular borders 4 4) Cribriform carcinoma with ductal differentiation 4 Abbreviation: PIN, prostate intraepithelial neoplasia.
Some authors have considered such different expressions as belonging to distinct types of tumors (tubular carcinomas, cribriform carcinomas, and ductal carcinomas),[17] but such an elaborate scheme appears to be unnecessary, because the different morphologic appearances may be simply considered to be expressions of the variable grade of differentiation.