cri-du-chat syndrome

cri-·du-·chat syn·drome

, cri du chat syndromecat-cry syndrome

a disorder due to deletion of the short arm of chromosome 5, characterized by microcephaly, hypertelorism, antimongoloid palpebral fissures, epicanthal folds, micrognathia, strabismus, mental and physical retardation, and a characteristic high-pitched catlike whine.

Synonym(s): cat's cry syndrome, Lejeune syndrome

cri-du-chat syndrome

(crē-do͞o-shä′)

n.

A congenital chromosomal disorder marked by microcephaly, epicanthal folds, micrognathia, strabismus, psychomotor and intellectual disability, and a characteristic high-pitched cry.

An embryopathy which is more common in females, caused by a loss of the short arm of chromosome 5, occasionally due to a ring chromosome
Prognosis Lifespan relatively normal

cri-du-chat syndrome

Lejeune syndrome Pediatrics An embryopathy more common in ♀, due to loss of short arm of chromosome 5, occasionally due to a ring chromosome Clinical High-pitched feline mewing which often diminishes with age, low birth weight, mental and physical retardation, hypertelorism, hypotonia, microcephaly, micrognathia, epicanthal folds, a moon-like facies, low-set ears, congenital heart defects, short metacarpals and metatarsals, pes planus, and partial syndactyly Prognosis Lifespan relatively normal

cri-du-chat syn·drome

(krē-dū-shah' sin'drōm)

A disorder due to deletion of the short arm of chromosome 5, characterized by microcephaly, hypertelorism, antimongoloid palpebral fissures, epicanthal folds, micrognathia, strabismus, mental and physical retardation, and a characteristic high-pitched catlike whine.

[Fr. cat's cry]

Lejeune,

Jerôme J.L.M., French cytogeneticist, 1926–.

Lejeune syndrome - a disorder characterized by microcephaly, antimongoloid palpebral fissures, epicanthal folds, micrognathia, strabismus, mental and physical retardation, and a characteristic high-pitched catlike whine. Synonym(s): cri-du-chat syndrome

cri-du-chat syn·drome

(krē-dū-shah' sin'drōm)

Disorder characterized by microcephaly, hypertelorism, antimongoloid palpebral fissures, epicanthal folds, micrognathia, strabismus, mental and physical retardation, and a characteristic high-pitched catlike whine.