- Role of Proteomic Techniques in Discovering Gingival
Crevicular Fluid Biomarkers
Proinflammatory and Anti-Inflammatory Cytokines in Gingival
Crevicular Fluid and Serum of Patients With Rheumatoid Arthritis and Patients With Chronic Periodontitis.
The flap design was, a
crevicular incisions were made extending from the mesial interdental papilla of the first molar to the mesial interdental papilla of the lateral incisor on the corresponding side.
Different proteomic tools have been designed to analyze the body fluids like blood, saliva, serum, gingival
crevicular fluids etc.
Interestingly, GHRL levels in gingival
crevicular fluid have been shown to be decreased in periodontally-diseased patients.
Alternatively, inflammation may develop as a result of direct toxic effects of concentrated drug in gingival
crevicular fluid and/ or bacterial plaques.
Gingival
crevicular fluid has been taken from the gingival sulcus before and after gingivectomy.
Increased levels of especially active MMP-8 (aMMP-8), but not latent, inactive proform, have been found in periodontitis- and peri-implantitis-affected oral fluids (saliva, mouth rinse, gingival
crevicular fluid (GCF), and periimplant sulcular fluid (PISF)) [8-10].
Goularte, "Association among pain, masticatory performance, and proinflammatory cytokines in
crevicular fluid during orthodontic treatment," American Journal of Orthodontics and Dentofacial Orthopedics, vol.