cretinism


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cretinism

 [kre´tĭ-nizm]
arrested physical and mental development with dystrophy of bones and soft tissues, due to congenital lack of thyroid gland secretion from hypofunction or absence of the gland. Affected children have a large head, short limbs, puffy eyes, coarse hair, a round abdomen, a thick and protruding tongue with drooling, excessively dry skin, lack of coordination, and mental retardation. Thyroid deficiency that is acquired or seen in adults is called myxedema. Administration of thyroid hormone medication, which must be continued for life, can result in normal growth and mental development of these children. If untreated, however, they will become permanently dwarfed, probably mentally retarded, and sterile.

cre·tin·ism

(kreh'tin-izm),

cretinism

(krēt′n-ĭz′əm)
n.
A congenital condition caused by a deficiency of thyroid hormone during prenatal development and characterized by small stature, intellectual disability, dystrophy of the bones, and a low basal metabolism.

cre·tin·ism

(kret'in-izm)
Obsolete term for congenital hypothyroidism.
See also: infantile hypothyroidism

cretinism

A condition caused by thyroid underaction from severe iodine deficiency early in life. It features dwarfism, mental retardation, dry skin, a large tongue and a puffy face. Cretinism occurs mainly in regions remote from the sea. Iodization of table salt and early screening of babies has largely eliminated the condition from such regions.

Cretinism

Severe hypothyroidism that is present at birth and characterized by severe mental retardation.

cre·tin·ism

(kret'in-izm)
Obsolete term for congenital hypothyroidism. This offensive term should be avoided.
References in periodicals archive ?
[4] In India, about 167 million people live at risk of IDD, of whom 54 million suffer from goiter, 2 million suffer from cretinism, and 6.6 million children have neurological deficits.
Endemic goiter and endemic cretinism. New York: Wiley; 1980: p.445-60.
The disorders include Hypothyroidism, Hyperthyroidism, Goitre, Thyroiditis, Cretinism (Congenital hypothyroidism), thyroid cancer etc.
When Professor Oxnard and fellow Oz researchers suggested in 2008 that the skull showed evidence of endemic dwarf cretinism resulting from congenital hypothyroidism and were not a new species of human, their claim caused controversy.
Role of cassava in the etiology of endemic goiter and cretinism. Report on International Development Research Centre.
Epidemiological survey of endemic goitre and endemic cretinism. New Delhi: Indian Council of Medical Research; 1989.
This condition, known as cretinism, leads to short stature and reduced brain size.
Had one not proof that such a patient had been previously fine-featured, well-formed, and active, it would be natural to suppose that it was an original defect such as is common in mild cretinism ...
Cretinism, I know, is an unpleasant condition, but if the highly-trained journalist in question picks up a dictionary, he'll see that there are two definitions for the word cretin.
Iodine is essential for normal growth and development; deficiency can lead to infantile myxedema (cretinism), miscarriage, goiter, increased perinatal mortality, reduced capacity for learning, and diminished physical and mental energy, according to PAHO.
Towards the eradication of endemic goiter, cretinism, and iodine deficiency.
And the Federal Aviation Administration will provide future students of institutional cretinism with astonishing seams of material.