crenation


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crenation

 [kre-na´shun]
1. the formation of abnormal notching around the edge of an erythrocyte (burr cell).
2. the notched appearance of an erythrocyte due to its shrinkage after suspension in a hypertonic solution.

cre·na·tion

(krē-nā'shŭn),
The process of becoming, or state of being, crenated.

crenation

(krĭ-nā′shən)
n.
1. A rounded projection, as on the margin of a shell.
2. The condition or state of being crenate.
3. A process resulting from osmosis in which red blood cells, in a hypertonic solution, undergo shrinkage and acquire a notched or scalloped surface.
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Taking a reading too early is the most common cause of false-negative results with this analyte.[3] False negatives may also be noted with high specific gravity urines, since the crenation of leukocytes can prevent esterase release.[4] The contamination of the container by oxidizing agents may also produce false-positive results.
Stick 'em up: optimizing results with urinalysis dipsticks
Electron microscopy of the skin biopsy showed proliferation of vascular smooth-muscle cells, crenation of the internal elastic lamina and fragmentation of elastic fibres.
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy (CADASIL)

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