creatinine clearance


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Related to creatinine clearance: Creatinine clearance test, Serum creatinine

cre·at·i·nine clear·ance

measurement of the clearance of endogenous creatinine, used for evaluating the glomerular filtration rate.

creatinine clearance

Nephrology The ratio of the rate of creatinine excretion in urine to its concentration in serum, a value that reflects the body's ability to excrete creatinine; it is used to diagnose and monitor renal function

cre·at·i·nine clear·ance

(krē-at'i-nin klēr'ăns)
A mathematical calculation of the total amount of creatinine excreted in the urine over a period of time, usually 24 hours to test renal function. The calculation is: creatinine clearance (mL/minute) = urine creatinine concentration (mL/dL) × volume of urine (mL/24 hour) ÷ plasma creatinine concentration (mg/dL) × 1440 minute/24 hour.
References in periodicals archive ?
(a) demonstrates relationship between pulse pressure and creatinine clearance, (b) demonstrates relationship between age and creatinine clearance, and (c) demonstrates relationship between body mass index and creatinine clearance.
Compared to day 0, there was a significant improvement in the renal function in group 1 compared to group 2 in terms of the mean change in creatinine (-0.8 [+ or -] 0.78 versus 0.39 [+ or -] 0.81 mg/dl, p < 0.0001), percent change in creatinine (-33 [+ or -] 26 versus 12 [+ or -] 39%, p = 0.0003), creatinine clearance (31 [+ or -] 39 versus 6 [+ or -] 34 mL/min, p = 0.0048), and percent changes in creatinine clearance (78 [+ or -] 93 versus 8 [+ or -] 64%, p = 0.002) (Table 4).
[3] Nonstandard abbreviations: GFR, glomerular filtration rate; MDRD-IDMS, Modification of Diet in Renal Disease-isotope dilution mass spectrometry; CKD-EPI, Chronic Kidney Disease Epidemiology Collaboration; CrCl, creatinine clearance; CG, CockcroftGault; sCr, serum creatinine; CysC, cystatin C; KDIGO, Kidney Disease: Improving Global Outcomes.
Key words: Chronic kidney disease creatinine clearance coronary revascularization percutaneous coronary intervention coronary artery bypass graft.
Arisz, "Creatinine clearance during cimetidine administration for measurement of glomerular filtration rate," The Lancet, vol.
Key Words: Serum Cystatin C; Diabetic Nephropathy; Estimated Creatinine Clearance; Estimated Glomerular Filtration Rate
* Baseline urinalysis and calculated creatinine clearance or eGFR are especially important in blacks with HIV and people with advanced HIV infection or comorbid conditions because these groups run a higher risk of nephropathy.
The urinary variables measured were diuresis, glucose, creatinine clearance (IL 300 plus, clinical chemistry analyzer), proteinuria, and microalbuminuria (Albumin Rat ELISA Kit, Abcam).
Thus, pharmacokinetic modeling of an exogenous plasma creatinine clearance could be useful for assessing renal creatinine excretion in birds.
Potential explanatory covariables might include patient's age, weight, gender, height, and creatinine clearance. The change in the NONMEM objective function produced by the inclusion of a covariate term was used to compare alternative models.
Exclusion criteria were defined as follows: patients younger than four years (considering difference in renal function related to age and different parameters for assessment of creatinine clearance), patients without sequential creatinine measurements suitable for analysis, and patients with high levels of baseline creatinine, according to the established criteria.

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