creatine kinase isoenzyme

creatine kinase isoenzyme

An isoenzyme, designated CK-MM–skeletal muscle, CK-MB-cardiac muscle and CK-BB-brain; CK is ↑ in serum when tissue suffers trauma or infarction. See CK-MB, Troponin.
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s pct (or equivalent) strips to the vidas series analyzer for the quantitative determination of the mv creatine kinase isoenzyme - vidas ck-mb (or similar)
A-C, Concentrations of cardiac troponin I (cTnI), creatine kinase isoenzyme (cK-MB), and myoglobin (Mb) in serum were detected by ELISA.
At that time, total creatine kinase and lactate dehydrogenase enzyme activity assays were commonly used, and creatine kinase isoenzyme (M, muscle; B, brain; CK-MB) measured as either enzyme activity or protein mass was considered the most clinically sensitive and specific biomarker for MI diagnosis.
Myocardial enzyme levels, including troponin I, creatine kinase isoenzyme MB, and myoglobin, were within normal level.
Creatine kinase isoenzyme patterns in human tissue obtained at surgery.
1 2 3 Leukocyte count, x [10.sup.9]/L 2.95 3.74 2.89 % Neutrophils 80.4 76.7 78.6 % Lymphocytes 13.5 18.2 15.4 Platelet count, x [10.sup.9]/L 71 82 172 Aspartate aminotransferase, U/L 86 77 45 Lactate dehydrogenase, U/L 886 492 209 Creatine phosphokinase, U/L 170 1,854 170 Creatine kinase isoenzyme MB, U/L 18 31 7 Laboratory variable Case- Reference patient no.
(4) Testing may include various combinations of cardiac-specific troponin (cTn) I or T, creatine kinase isoenzyme MB (CK-MB), and myoglobin (MYO) and multimarker panels (cTn, CK-MB, and MYO).
Creatine kinase isoenzyme activities in men and women following a marathon race.
Time Marker Late 1950s Aspartate aminotransferase (AST, SGOT) 1960s Creatine kinase (CK, CPK (a)) 1970s Creatine kinase isoenzyme (CK-MB activity) 1970s Lactate dehydrogenase isoenzymes (ratio of LD1 to LD2) Late 1980s CK-MB mass concentration Mid-1990s cTnI, cTnT (a) CPK, creatine phosphokinase; LD1, lactate dehydrogenase fraction 1; LD2, lactate dehydrogenase fraction 2.
To prove the feasibility of their technology, the authors used an in vivo murine model to measure markers of myocardial injury (myoglobin, creatine kinase isoenzyme MB, and cardiac troponin I) that involved subcutaneous placement of a sensor containing the nanoparticles within a semipermeable membrane placed in the animal's flank.
(3) serves as a useful benchmark in this context because it is focused on a clinical indication (cardiac damage markers) in which numerous proteins, such as creatine kinase isoenzyme MB, troponins, and B-type natriuretic peptide, have achieved undisputed clinical success.
In the mid-1980s, Ladenson's laboratory developed monoclonal antibodies that were specific for the creatine kinase isoenzyme MB (CK-MB).