creatine kinase
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Related to creatine kinase: creatinine, Creatine Kinase Test
creatine
[kre´ah-tin]a nonprotein substance synthesized in the body from three amino acids: arginine, glycine (aminoacetic acid), and methionine. Creatine readily combines with phosphate to form phosphocreatine, or creatine phosphate, which is present in muscle, where it serves as the storage form of high-energy phosphate necessary for muscle contraction.
creatine kinase an enzyme catalyzing the transfer of a phosphate group from phosphocreatine to ATP. It has three isoenzymes: CK1, found primarily in the brain; CK2, found in the myocardium; and CK3, found in both skeletal muscle and the myocardium. The presence of CK2 in the blood is strongly indicative of a recent myocardial infarction; it is present until about 72 hours after the attack.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
cre·a·tine ki·nase (CK),
an enzyme catalyzing the reversible transfer of phosphate from phosphocreatine to ADP, forming creatine and ATP; of importance in muscle contraction. Certain isozymes are elevated in plasma following myocardial infarctions.
Synonym(s): creatine phosphokinase
Farlex Partner Medical Dictionary © Farlex 2012
creatine kinase
n.
An enzyme present in muscle, brain, and other tissues of vertebrates that catalyzes the reversible conversion of ADP and phosphocreatine into ATP and creatine.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
creatine kinase
Creatine phosphokinase Internal medicine An 82 kD dimeric enzyme that catalyzes the reaction ATP + creatine = ADP + phosphocreatine, which exchanges high-energy phosphate and consumes energy; CK is concentrated in skeletal muscle, heart, brain; since CK levels peak 12-24 hrs after an MI and returns to normal by 48 hrs, specimen timing is critical Ref range 0-250 U/L. See Creatinine kinase isoenzymes.McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
cre·a·tine ki·nase
(CK) (krē'ă-tin kī'nās)An enzyme catalyzing the reversible transfer of phosphate from phosphocreatine to ADP, forming creatine and ATP; of importance in muscle contraction. Certain isozymes are elevated in plasma following myocardial infarctions.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
cre·a·tine ki·nase
(CK) (krē'ă-tin kī'nās)An enzyme catalyzing the reversible transfer of phosphate from phosphocreatine to adenosine diphosphate, forming creatine and adenosine triphosphate.
Medical Dictionary for the Dental Professions © Farlex 2012