creatine kinase


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Related to creatine kinase: creatinine, Creatine Kinase Test

creatine

 [kre´ah-tin]
a nonprotein substance synthesized in the body from three amino acids: arginine, glycine (aminoacetic acid), and methionine. Creatine readily combines with phosphate to form phosphocreatine, or creatine phosphate, which is present in muscle, where it serves as the storage form of high-energy phosphate necessary for muscle contraction.
creatine kinase an enzyme catalyzing the transfer of a phosphate group from phosphocreatine to ATP. It has three isoenzymes: CK1, found primarily in the brain; CK2, found in the myocardium; and CK3, found in both skeletal muscle and the myocardium. The presence of CK2 in the blood is strongly indicative of a recent myocardial infarction; it is present until about 72 hours after the attack.

cre·a·tine ki·nase (CK),

an enzyme catalyzing the reversible transfer of phosphate from phosphocreatine to ADP, forming creatine and ATP; of importance in muscle contraction. Certain isozymes are elevated in plasma following myocardial infarctions.

creatine kinase

n.
An enzyme present in muscle, brain, and other tissues of vertebrates that catalyzes the reversible conversion of ADP and phosphocreatine into ATP and creatine.

creatine kinase

Creatine phosphokinase Internal medicine An 82 kD dimeric enzyme that catalyzes the reaction ATP + creatine = ADP + phosphocreatine, which exchanges high-energy phosphate and consumes energy; CK is concentrated in skeletal muscle, heart, brain; since CK levels peak 12-24 hrs after an MI and returns to normal by 48 hrs, specimen timing is critical Ref range 0-250 U/L. See Creatinine kinase isoenzymes.

cre·a·tine ki·nase

(CK) (krē'ă-tin kī'nās)
An enzyme catalyzing the reversible transfer of phosphate from phosphocreatine to ADP, forming creatine and ATP; of importance in muscle contraction. Certain isozymes are elevated in plasma following myocardial infarctions.

cre·a·tine ki·nase

(CK) (krē'ă-tin kī'nās)
An enzyme catalyzing the reversible transfer of phosphate from phosphocreatine to adenosine diphosphate, forming creatine and adenosine triphosphate.
References in periodicals archive ?
Serum creatine kinase levels in overt and subclinical hypothyroidism.
In the first household, the adult sister (patient G) and mother (patient H) of the index patient both had eosinophila, elevated creatine kinase levels, and positive Trichinella IgG results by ELISA; both patients were classified as having confirmed cases of trichinellosis.
Muscle-type MM creatine kinase is specifically boundto sarcoplasmic reticulum and can support Ca2+ uptake and regulate local ATP/ADP ratios.
Symptoms following atypical antipsychotics include fewer extrapyramidal symptoms, reduced creatine kinase elevations, reduced muscle rigidity, and frequent mild fever.
There was no effect of condition on isometric peak torque, concentric peak torque, jump performance, creatine kinase concentration and muscle soreness at any time point.
Routine measurement of creatine kinase is neither helpful nor cost effective for detecting rare cases of myopathy who are on standard doses of statin.
The first of all was soft spirit, silence, no fever, sweating, normal level of white blood cells and creatine kinase in the results of laboratory examination.
Role of creatine kinase isoenzymes on muscular and cardiorespiratory endurance.
In the reaction creatine kinase catalyzes the transfer of a phosphate group from the creatine phosphate substrate to adenosine diphosphate (ADP).
Influence of speed training loads on the activity of creatine kinase and lactic dehydrogenase and the concentration of oxypurines in blood samples of young football players.