coumarin

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coumarin

 [koo´mah-rin]
1. a principle extracted from the tonka bean, from which several anticoagulants are derived that inhibit hepatic synthesis of vitamin K–dependent coagulation factors.
2. any of these derivatives.

cou·ma·rin

(kū'mă-rin),
1. A general descriptive term applied to anticoagulants and other drugs derived from dicumarol, a component of the Tonka bean.
2. A fragrant neutral principle obtained from the Tonka bean, Dypterix odorata, and made synthetically from salicylic aldehyde; it is used to disguise unpleasant odors.
[coumarou, native name of Tonka bean]

coumarin

/cou·ma·rin/ (koo´mah-rin)
1. a principle extracted from the tonka bean; it contains a factor, dicumarol, that inhibits hepatic synthesis of vitamin K–dependent coagulation factors, and a number of its derivatives are used as anticoagulants in treating disorders characterized by excessive clotting.
2. any of these derivatives or any synthetic compound with similar activity.

coumarin

(ko͞o′mər-ĭn)
n.
A fragrant crystalline compound, C9H6O2, present in tonka beans and produced synthetically for use as a fragrance. Coumarin has been banned as a food additive in the United States because it can be toxic in large amounts.

cou′ma·ric (-mər-ĭk) adj.

coumarin

[ko̅o̅′mərin]
a class of orally active anticoagulant agents with warfarin as its prototype.
indications It is prescribed for prophylaxis and treatment of thrombosis and embolism.
contraindications Known hypersensitivity to the drug prohibits its use. It is not prescribed to patients who are at risk for hemorrhage or who are pregnant.
adverse effects The most serious adverse reaction is hemorrhage. Many other drugs interact with this drug to increase or decrease its effect.

cou·ma·rin

(kū'mă-rin)
Fragrant neutral principle obtained from the Tonka bean, Dypterix odorata, and also made synthetically from salicylic aldehyde; used to disguise unpleasant odors.

coumarin,

n C9H6O, derived from a variety of sources, including tonka bean and sweet clover; may also be artificially manufactured.
Enlarge picture
Coumarin.

cou·ma·rin

(kū'mă-rin)
A general descriptive term applied to anticoagulants and other drugs derived from dicumarol.

coumarin

1. a principle extracted from the tonka bean, from which several anticoagulants are derived, that inhibits hepatic synthesis of vitamin K-dependent coagulation factors.
2. any of these derivatives.
3. see also dicoumarol.
References in periodicals archive ?
extracts: chlorogenic acid, syrigin, procyanidin B2, caffeic acid, (-)-epicatechin, cinnamic acid, coumaric acid, phlorizin and quercetin, as described by others.
Volatile phenols are microbial-derived products formed from odorless precursors that are present in all grapes (ferulic and coumaric acids).
Nine phenolic acids (protocatechuic, p-hydroxybenzoic, ferulic, chlorogenic, vanillic, caffeic, vanillin, o- and p- coumaric acids) were extracted, separated, and quantified by HPLC-DAD.
Quercetin, catechin, ferrulic acid, caffeic acid, gallic acid, coumaric acid, and rutin, are among the most common naturally occurred antioxidant phenolic compounds in foods.
They found that the activity of ferulic acid was greater than that of coumaric acid, which was greater than that of propyl gallate.
Although more than 300 constituents have been identified in propolis samples, biological activity is mainly due to a few substances, such as flavonoids, terpenes, caffeic, ferulic and coumaric acids and esters.
27) There is significant variation in the levels of both PPO and caftaric and coumaric acids in cultivars, and therefore the tendency to brown varies.
Methanol and ethyl acetate extracts of the yellow sweet cherry "Rainier" containing beta-carotene, ursolic, coumaric, ferulic and cafeic acids inhibited LPO by 78 and 79%, respectively, at 250 microg/mL.
2009) affirmed that wild poinsettia seeds show great resistance to known allelochemicals such as rutin, quercetin, aconitic acid, ferulic acid, coumaric acid, vanillic acid and eucaliptol.
Abbreviations: CA, coumaric acid; CIMMYT, International Maize and Wheat Improvement Center; DiFA, diferulic acid; FA, ferulic acid; HRGP, hydroxyproline-rich glycoprotein; MDT, median development time; MW, maize weevil; P, population.
The standard extract contains more than 17% coumarin and parts of coumaric acid and hydrocoumarin.