cotrimoxazole


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cotrimoxazole

Bactrim®, Septra®, Sulfatrim®, Cotrim®, smx-tmp, tmp-smx Infectious disease A combination of 2 antimicrobials–sulfamethoxazole & trimethoprim, used for bacterial and protozoal infections. See Trimethoprim-sulfamethoxazole.
References in periodicals archive ?
Guidelines on Post-Exposure Prophylaxis for HIV and the Use of Cotrimoxazole Prophylaxis for HIV-Related Infections Among Adults, Adolescents and Children: Recommendations for a Public Health Approach.
In the BAN study, prescriptions for amoxicillin accounted for 1,932 (37.8%) of all antibacterial drug prescriptions for HIV-exposed, uninfected infants, followed by cotrimoxazole (23.4%), tetracycline (8.7%), erythromycin (8.2%), and chloramphenicol (6.0%).
gonorrhoeae showed moderate to high resistance (60 to 88%) to conventional antibiotics; penicillin (88%), tetracycline (80%), cotrimoxazole (80%), erythromycin (72%), ciprofloxacin (68%) and cefixime (60%).
The most predominant Gram positive isolates (Bacillus spp.) showed highest (75%) and least (5%) susceptibility to Gentamicin and Cotrimoxazole respectively.
[1] The organisms showed a moderate-to-high resistance to cephalosporins, aminoglycosides, fluoroquinolones, tetracycline, cotrimoxazole and ticarcillin/clavulanic acid.
Other than that, for all other antibiotics such as piperacillin-tazobactam, cefotaxime, ceftazidime, tetracycline, cotrimoxazole, aztreonam, and gentamicin isolates showed complete resistance 20/20 (100%) [Table 2].
Resistance by disk diffusion technique noted in Salmonella Paratyphi A was ampicillin 60%, chloramphenicol 40%, cotrimoxazole 38%, ceftriaxone 7.9%, ciprofloxacin 8%, cefpodoxime 7.9%, imipenem and ertapenem 2.6%, aztreonam 1.3%, moxifloxacin 6.6%, and gatifloxacin 1.3%.
One hundred seventy-three (33.4%) of respondents were taking Cotrimoxazole prophylaxis of which 116 (67.0 %%) of them took for less than six years.
The antibiotics tested in this study include ampicillin (10 [micro]g), cefixime (5 [micro]g), ceftriaxone (30 [micro]g), nalidixic acid (30 [micro]g), ciprofloxacin (5 [micro]g), levofloxacin (5 [micro]g), chloramphenicol (30 [micro]g), cotrimoxazole (25 [micro]g), azithromycin (15 [micro]g), and tetracycline (30 [micro]g), respectively.
She consulted the HIV treatment center for the headache where she was treated empirically for cerebral toxoplasmosis with cotrimoxazole for six weeks without any improvement of the headaches.
Cotrimoxazole prophylaxis for opportunistic infections (toxoplasmosis, pneumocystis) was found in 61% (25/41) of patients.