Guidelines on Post-Exposure Prophylaxis for HIV and the Use of Cotrimoxazole
Prophylaxis for HIV-Related Infections Among Adults, Adolescents and Children: Recommendations for a Public Health Approach.
In the BAN study, prescriptions for amoxicillin accounted for 1,932 (37.8%) of all antibacterial drug prescriptions for HIV-exposed, uninfected infants, followed by cotrimoxazole
(23.4%), tetracycline (8.7%), erythromycin (8.2%), and chloramphenicol (6.0%).
gonorrhoeae showed moderate to high resistance (60 to 88%) to conventional antibiotics; penicillin (88%), tetracycline (80%), cotrimoxazole
(80%), erythromycin (72%), ciprofloxacin (68%) and cefixime (60%).
The most predominant Gram positive isolates (Bacillus spp.) showed highest (75%) and least (5%) susceptibility to Gentamicin and Cotrimoxazole
 The organisms showed a moderate-to-high resistance to cephalosporins, aminoglycosides, fluoroquinolones, tetracycline, cotrimoxazole
and ticarcillin/clavulanic acid.
Other than that, for all other antibiotics such as piperacillin-tazobactam, cefotaxime, ceftazidime, tetracycline, cotrimoxazole
, aztreonam, and gentamicin isolates showed complete resistance 20/20 (100%) [Table 2].
Resistance by disk diffusion technique noted in Salmonella Paratyphi A was ampicillin 60%, chloramphenicol 40%, cotrimoxazole
38%, ceftriaxone 7.9%, ciprofloxacin 8%, cefpodoxime 7.9%, imipenem and ertapenem 2.6%, aztreonam 1.3%, moxifloxacin 6.6%, and gatifloxacin 1.3%.
In this study, cotrimoxazole
is the most commonly prescribed drug (58.7%).
One hundred seventy-three (33.4%) of respondents were taking Cotrimoxazole
prophylaxis of which 116 (67.0 %%) of them took for less than six years.
The antibiotics tested in this study include ampicillin (10 [micro]g), cefixime (5 [micro]g), ceftriaxone (30 [micro]g), nalidixic acid (30 [micro]g), ciprofloxacin (5 [micro]g), levofloxacin (5 [micro]g), chloramphenicol (30 [micro]g), cotrimoxazole
(25 [micro]g), azithromycin (15 [micro]g), and tetracycline (30 [micro]g), respectively.
She consulted the HIV treatment center for the headache where she was treated empirically for cerebral toxoplasmosis with cotrimoxazole
for six weeks without any improvement of the headaches.
prophylaxis for opportunistic infections (toxoplasmosis, pneumocystis) was found in 61% (25/41) of patients.