These statements involve inherent risks and uncertainties that could cause actual results to differ materially from those projected or anticipated, including risks related to regulatory approval and clinical development of long-acting cosyntropin
, expectations regarding royalties to be received based on sales of NUCYNTA and NUCYNTA ER, expectations regarding potential business opportunities and other risks outlined in the Company's public filings with the Securities and Exchange Commission, including the Company's most recent annual report on Form 10-K and subsequent Quarterly Reports on Form 10-Q.
Assertio Therapeutics announced that it has submitted to the FDA a 505 new drug application for its novel injectable formulation of cosyntropin
depot with its partner, West Therapeutic Development.
can be injected to stimulate release of ACTH.
11-Deoxycortisol maybe superior to cortisol in confirming a successful adrenal vein catheterization without cosyntropin
: a pilot study.
A screening serum 17-OHP level of > 6 nmol/L was an indication to obtain a complete adrenocortical profile and to perform a highdose (250 [micro]g) cosyntropin
stimulation test (HDSST).
Administration of cosyntropin
(1-24 ACTH; Cortrosyn) to directly stimulate adrenal cortisol release is the most commonly used diagnostic test to evaluate adrenal function.
Shimshi, "Diagnosing adrenal insufficiency: which test is best-the 1-microg or the 250-microg cosyntropin
stimulation test?," Endocrine Practice, vol.
test can help distinguish between primary and secondary adrenal insufficiency.
under which Depomed will acquire from SlAaAaAeA n rights to market t specialty drug, cosyntropin
(Synthetic ACTH Depot) in the United States and divest its Lazanda (fentanyl) nasal spray CII to SlAaAaAeA n, the compa said.
under which Depomed will acquire from SlAaAaAeAaAaAeAeA n rights to market specialty drug, cosyntropin
(Synthetic ACTH Depot) in the United States and divest its Lazanda (fentanyl) nasal spray CII to SlAaAaAeAaAaAeAeA n, the com said.
stimulation testing results show low cortisol, dehydroepiandrosterone (DHEA), dehydroepiandrosterone sulfate (DHEA-S) and 17-OH progesterone but high, DOC and corticosterone levels and reveal the adrenal steroidogenic defect (1).