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1. a hormone secreted by the anterior lobe of the pituitary gland that stimulates the cortex of the adrenal gland to secrete its hormones, including corticosterone. If production of corticotropin falls below normal, the adrenal cortex decreases in size, and production of the cortical hormones declines.
2. a pharmaceutical preparation of animal-derived corticotropin, administered intravenously for diagnostic testing of adrenocortical function and subcutaneously or intramuscularly, in a slowly absorbed gel form (repository corticotropin), as an anticonvulsant for treating infantile spasms. Called also adrenocorticotropic hormone (ACTH), adrenocorticotropin, and corticotrophin.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
corticotrophinCorticotropin, adrenocorticotrophic hormone (ACTH), a hormone produced by the PITUITARY GLAND which stimulates the adrenal cortex to secrete steroids in response to stress.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
corticotrophinSee ADRENOCORTICOTROPIC HORMONE.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005
A hormone that acts on cells of the adrenal cortex, causing them to produce male sex hormones and hormones that control water and mineral balance in the body.
Mentioned in: Pituitary Dwarfism
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.