corticotrophin


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corticotropin

 [kor″tĭ-ko-tro´pin]
1. a hormone secreted by the anterior lobe of the pituitary gland that stimulates the cortex of the adrenal gland to secrete its hormones, including corticosterone. If production of corticotropin falls below normal, the adrenal cortex decreases in size, and production of the cortical hormones declines.
2. a pharmaceutical preparation of animal-derived corticotropin, administered intravenously for diagnostic testing of adrenocortical function and subcutaneously or intramuscularly, in a slowly absorbed gel form (repository corticotropin), as an anticonvulsant for treating infantile spasms. Called also adrenocorticotropic hormone (ACTH), adrenocorticotropin, and corticotrophin.

corticotrophin

/cor·ti·co·tro·phin/ (kor´tĭ-ko-tro″fin) corticotropin.

corticotrophin

Corticotropin, adrenocorticotrophic hormone (ACTH), a hormone produced by the PITUITARY GLAND which stimulates the adrenal cortex to secrete steroids in response to stress.

corticotrophin

See ADRENOCORTICOTROPIC HORMONE.

Adrenocorticotropin (corticotrophin)

A hormone that acts on cells of the adrenal cortex, causing them to produce male sex hormones and hormones that control water and mineral balance in the body.
Mentioned in: Pituitary Dwarfism

corticotrophin

References in periodicals archive ?
Hypothalamic cocaine- and amphetamine-regulated transcript and corticotrophin releasing factor neurons are stimulated by extracellular volume and osmotic changes.
Treatment of acute exacerbations with corticotrophin (ACTH).
37) Other neuroendocrine substances and structures involved include, but not limited to, serotonin, norepinephrine, N-methyl-D-aspartate receptors, opioid peptide receptors, [gamma]-Aminobutyric acid (GABA) systems, dynorphin, acetylcholine, corticotrophin releasing factor, adrenocorticotropic hormone, and corticosterone.
MRI--magnetic resonance imaging, ACTH--adrenal corticotrophin thyroid hormone, CT scan--computadorizred tomography.
The first contributes to the secretion of two corticotrophin hormones, "follicle stimulating hormone (FSH) and luteinizing hormone (LH)," both necessary for menstruation.
Weinstock (2008) explored the effect of stress-induced levels of cortisol and corticotrophin releasing hormone in pregnancy.
They were found to have higher levels of corticotrophin and cortisol than did normal controls, indicating that they have an overactive hypothalamic-pituitary adrenal (HPA) axis (20).
The effect of smoking on the time course release of catecholamines, corticotrophin releasing hormone (CRH), adrenocorticotrophin hormone (ACTH), and cortisol in pregnancy.
Examples: Erythropoietin (EPO), growth hormones and corticotrophin.
In addition, NA stimulation is associated with the lightening of types of sleep other than REM and increased levels of corticotrophin releasing factor (CRF).
The activation of 5HT2 receptors in the Leydig cells by serotonin provokes a cascade of autocrine events that promote the intratesticular increase of corticotrophin releasing hormone (CRH) and b-endorphin (Dufau et al.
The precursor to cortisol, corticotrophin releasing factor (CRF), is utilized as a neural transmitter in some regions (Koob, 1999).