TMA-hemolytic uremic syndrome (TMA-HUS) and renal cortical necrosis
are the most important intrinsic causes of AKI associated with P.
Contrast enhanced ultrasound (CEUS) in the diagnosis of post-partum bilateral renal cortical necrosis
: A case report and review of the literature.
TMA and Renal Cortical Necrosis. Acute renal failure is a frequently reported complication of snakebites.
In our case, given the lack of clear mechanism for TMA, presence of extensive renal cortical necrosis, oliguria, and dialysis dependence, along with no evidence of benefit, plasmapheresis was not attempted.
Renal biopsy was carried out in 15 patients, findings were acute tubular necrosis in 6, cortical necrosis
in 4, tubulointerstitial nephritis in 2 and 2 had crescentic glomerulonephritis.
Acute cortical necrosis
is rare in patients with acute kidney injury from malaria (15).
(1-5) Our patient suffered from both diseases, as evidenced by histological analyses: cortical necrosis
and signs of thrombotic microangiopathy (fibrin-platelet thrombus material within the glomerular capillary lumina) and abnormal clotting parameters with low fibrinogen, high D-dimer levels and low platelet counts.
Rat studies showed that serotype 3 leads to cortical necrosis
, while serotype 9V causes subcortical abscesses and little to no damage in the cerebral cortex, Dr.
The neurological signs are due to ipsilateralleptomeningealangioma involving the occipital and posterior parietal lobes of the brain; vascular stasis with resultant is chaemialeads to calcification and laminar cortical necrosis
. Management of the syndrome involves both medical and surgical approaches.
Microscopic examination revealed ovarian parenchyma with extensive oedema, and prominent cortical necrosis
, haemorrhage and foreign body giant cell reaction to faecal/vegetable material indicating bowel perforation or leakage with mixed inflammatory cell infiltration.
The neurological signs are due to ipsilateral leptomeningeal angioma involving the occipital and posterior parietal lobes of the brain; vascular stasis with resultant ischemia leads to calcification and laminar cortical necrosis
Glomerular collapse in association with acute cortical necrosis
in native kidneys: all that collapses is not idiopathic collapsing glomerulopathy.