cortical dysplasia

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cor·ti·cal dys·pla·si·a

a malformative disorganization of the cytoarchitecture of the cortex relative to neurons.
Farlex Partner Medical Dictionary © Farlex 2012
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Focal cortical dysplasia is among the most common causes of epilepsy attributable to focal cerebral dysgenesis; 60% FCD is found in temporal lobes.
Pathological investigation revealed focal cortical dysplasia. After surgery one of them had one seizure per month under multiple antiepileptic drug treatments.
[16] In a study by the University of California, Los Angeles (UCLA) group [17] it was shown that children with cortical dysplasia have a slightly higher recurrence rate than other patients with epilepsy, but it is clear that early surgery, before 3 years of age, makes a significant difference and leads to lower seizure recurrence rates.
Cerebellar cortical dysplasia: MRI aspects and significance.
The six cases treated had to do with mesial temporal sclerosis, right temporal cystic lesion, right temporal cavernoma, and cortical dysplasia, he said, noting that patients suffering from epilepsy are treated in stages.
There also are reports of increased MAP-2 expression in the cerebral cortex of patients with early stage Alzheimer's disease (Mukateba-Ladinska et al., 2000) and in the pyramidal neurons of the cerebral cortex of patients with cortical dysplasia associated with cases of intractable epilepsy (Yamanouchi et al., 1996).
In individuals with epilepsy, thin-section 3D coronal oblique T1 gradient echo and coronal oblique T2 series are added to assess for more subtle abnormalities, including hippocampal sclerosis or cortical dysplasias. High-resolution 3D sequences and T2 FLAIR (FLuid Attenuated Inversion Recovery) images increase the sensitivity to subtle cortical dysplasia and other abnormalities, including neoplasms.
Hauptman et al., "Assessment and surgical outcomes for mild type i and severe type II cortical dysplasia: a critical review and the UCLA experience," Epilepsia, vol.
Jude has cortical dysplasia, a congenital brain abnormality which has resulted in severe and complex epilepsy and learning disabilities.
Erik Ortiz Cruz, a 10-month old Real fan, has cortical dysplasia aACAo a brain abnormality that causes up to 30 seizures each day.
By January of 2012, he had been diagnosed with a mild form of cortical dysplasia, a common cause of pediatric epilepsy, but the descent in his health indicated bigger problems were at play.
They claim an operation at three years old would have cured his cortical dysplasia condition, saving him from hundreds of epileptic fits.