deoxycorticosterone

desoxycorticosterone

 [des-ok″sĭ-kor″tĭ-ko-stēr´ōn]

a mineralocorticoid with no glucocorticoid activity, secreted in small amounts by the human adrenal cortex. It is used with a glucocorticoid for replacement therapy in adrenocortical insufficiency and addison's disease and for treatment of salt-losing adrenogenital syndrome.

de·ox·y·cor·ti·cos·ter·one (DOC),

(dē-oks'ē-kōr'ti-kos'tĕr-ōn),

An adrenocortical steroid, principally a biosynthetic precursor of corticosterone, which occasionally appears in adrenocortical secretions; a potent mineralocorticoid with no appreciable glucocorticoid activity.

Synonym(s): 21-hydroxyprogesterone, cortexone, deoxycortone, desoxycortone

deoxycorticosterone

(dē-ŏk′sē-kôr′tĭ-kŏs′tə-rōn′)

n.

A steroid hormone, C₂₁H₃₀O₃, secreted by the adrenal cortex or produced synthetically and formerly used to treat adrenal insufficiency.

deoxycorticosterone

Endocrinology An adrenal steroid with potent mineralocorticoid properties, and minimal glucocorticosteroid properties ↑ in Congenital adrenal hyperplasia, Cushing syndrome, primary aldosteronism, low renin HTN, adrenal CA ↓ in Adrenal insufficiency or hypoplasia

de·ox·y·cor·ti·co·ster·one

(dē-oks'ē-kōr-ti-kos'tĕr-ōn)

An adrenocortical steroid, principally a biosynthetic precursor of corticosterone and possibly aldosterone, which rarely appears in adrenocortical secretions; a potent mineralocorticoid with no appreciable glucocorticoid activity.
Compare: bioregulator
Synonym(s): 21-hydroxyprogesterone.

de·ox·y·cor·ti·co·ster·one

(dē-oks'ē-kōr-ti-kos'tĕr-ōn)

Potent mineralocorticoid with no appreciable glucocorticoid activity.

11-desoxycorticosterone, deoxycorticosterone, deoxycortone

one of the mineralocorticoids, adrenocortical steroids which lack a substituent at C-11; has a greater effect on electrolyte metabolism than glucocorticoids. Available pharmaceutically as the acetate (DOCA), which is short-acting, and the pivalate (DOCP), a slow release form for use in the treatment of hypoadrenocorticism.