pylori -infected patients, with the progress of atrophic gastritis from the antrum to the corpus mucosa
, the amount of PG I is considerably reduced or abolished owing to the damage of principal cells and parietal cells, while the level of serum PG II increases because the infiltration model of neutrophils and mononuclear cells is toward the upper stomach from the antrum., One study concluded that PG II is independently associated with risk of gastric cancer. This evidence indicated that the serum PG level was closely correlated with the progression of atrophic gastritis. Meantime, it indirectly reflected the status of H.
As a result of screening to determine the following groups of patients: severe antral mucosa atrophy, moderate antral mucosa atrophy, mild antral mucosa atrophy, severe corpus mucosa atrophy, and other respondents of noninvasive screening of atrophic gastritis, the following criteria were used (Tables 1 and 2).
All patients were diagnosed with severe antral mucosa atrophy, moderate antral mucosa atrophy, mild antral mucosa atrophy, severe corpus mucosa atrophy, moderate corpus mucosa atrophy, and mild corpus mucosa atrophy with the technique of Pasechnikov et al.
The techniques for the detection of antral mucosal atrophy and corpus mucosa atrophy with no account taken of its severity, as well as severe antral mucosa atrophy and severe corpus mucosa atrophy, are taken as a standard, as they have been verified by a large number (450 patients) of comparative histological analyses.