coronary heart disease


Also found in: Dictionary, Thesaurus, Acronyms, Encyclopedia, Wikipedia.

coronary

 [kor´ah-nar-e]
encircling in the manner of a crown; said of anatomical structures such as vessels, ligaments, or nerves.
coronary arteries two large arteries that branch from the ascending aorta and supply all of the heart muscle with blood (see also table of arteries).
 A view of the coronary arterial system. The arteries serving the posterior aspect of the myocardium are shown here in a lighter shade.
coronary artery disease (CAD) atherosclerosis of the coronary arteries, which may cause angina pectoris, myocardial infarction, and sudden death. Both genetically determined and avoidable risk factors contribute to the disease; they include hypercholesterolemia, hypertension, smoking, diabetes mellitus, and low levels of high density lipoproteins (HDL).
coronary heart disease (CHD) ischemic heart disease.
coronary occlusion the occlusion, or closing off, of a coronary artery, usually caused by a narrowing of the lumen of the blood vessels by the plaques of atherosclerosis. Sometimes a plaque may rupture and release vasoactive or thrombogenic substances that lead to clot formation. If there is adequate collateral circulation to the heart muscle at the time of the occlusion, there may be little or no damage to the myocardial cells. When occlusion is complete, however, with no blood being supplied to an area of the myocardium, myocardial infarction results.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

coronary heart disease

A general term for any disease affecting the coronary arteries, in particular atherosclerosis.

Risk factors
Hypertension, smoking and high cholesterol.

Management
Lifestyle and related medical therapy.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
Association of helicobacter pylori infection with severity of coronary heart disease. ARYA Atheroscler.
In total, coronary heart disease kills about 4,300 people in Wales each year and most of these deaths are caused by a heart attack.
"It is not clear whether this relationship is due to confounding factors such as poor socioeconomic environment, or nutrition, during childhood that on the one hand determine achieved height and on the other the risk of coronary heart disease, or whether it represents a primary relationship between shorter height and more coronary heart disease.
A spokesman for Gateshead Council's public health team said: "This region has historically always had a high incidence of coronary heart disease, much of it attributed to lifestyle factors."
"These findings suggest that vertex baldness is more closely associated with systemic atherosclerosis (coronary heart disease) than with frontal baldness," said the study.
11.0%, 1.70 (1.03 - 2.80), p=0.04; coronary heart disease 16.3% v.
A meta-analysis published in the American Journal of Clinical Nutrition found that every additional ingested gram of ALA was associated with a 10% lower risk of death from coronary heart disease. The researchers believe ALA may have a direct or indirect antiarrythmic effect.
This study showed that periodontal disease is significantly associated with coronary heart disease and the levels of periodontal parameters were higher in smoker-diabetic coronary heart disease patients suggesting an association between periodontal disease, smoking, diabetes and coronary heart disease.
Diet plays an important role in the development of Coronary heart disease. Previously it was reported that high consumption of diet containing saturated fats such as beef fat, butter, cheese and other dairy products increases the risk of Coronary heart disease.3 Because of this association between saturated fatty acids and Coronary heart disease it was recommended that consumption of diet containing saturated fatty acids should be decreased or replaced by other diet containing poly unsaturated fatty acids like (soybean oil, corn oil and safflower oil, as well as fatty fish) to reduce the risk of CHD.
In addition, the rising consumption of sugar-sweetened beverages, which include soda, sports drinks, and fruit drinks, led to an estimated 1.4 million additional life-years burdened by diabetes and 50,000 additional life-years burdened by coronary heart disease in the first decade of the 21st century.
Decision Resources (Waltham, MA), one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that, despite the patent expiries by 2012 of the two sales-leading therapies, new product launches will drive an increase of $4.6 billion in the overall coronary heart disease market by 2017.
"Coronary heart disease doesn't discriminate wildly in terms of the age and character of the people it afflicts."