[3-6] The concept of hypocalcaemia-induced coronary artery vasospasm syndrome is contentious, as it seems unlikely that a single artery would undergo sufficient vasospasm to cause ischaemia, without another artery of similar calibre causing ischaemic symptoms at a distant site.
The diagnosis of hypocalcaemia-induced coronary artery vasospasm is difficult to make in the acute setting, especially in a patient with multiple risk factors such as CKD and HIV infection.
The most common cause of AMI is underlying coronary atherosclerosis; (1) however, AMI may occur due to in-situ thrombosis, thromboembolism, or coronary artery vasospasm
, especially due to cocaine or other substance abuse.
An immediate coronary angiography was performed which revealed diffuse coronary artery vasospasm
. Diffuse small caliber vessels were demonstrated in the left coronary artery (Figure 3(a)) and the right coronary artery (Figure 3(b)).
Some etiologies reported include coronary artery anomalies, cocaine-induced coronary artery vasospasm
, a hypercoagulable state related to the use of oral contraceptive pills, and diseases such as systemic lupus erythematosus, antiphospholipid antibody syndrome, Factor V Leiden mutation, and nephrotic syndrome (3-5).
To exclude the possibility of coronary artery vasospasm
, the patient who exhibited normal coronary anatomy underwent a hyperventilation test during the coronary arteriography.
Dobbs, "Coronary artery vasospasm
during awake deep brain stimulation surgery," British Journal of Anaesthesia, vol.
(1) Coronary artery vasospasm
is another rare manifestation associated with CSS.
A Case of Acute Myocardial Infarction with ST-Segment Elevation in a Lead Augmented Right Vector Caused by a Left Main Coronary Artery Vasospasm
. Korean Circ J.
The abnormal, antemortem EKG findings were attributed to a myocardial infarct resulting from coronary artery vasospasm
, a well-known complication of cocaine abuse.
SUMAVEL DosePro is contraindicated in patients with uncontrolled hypertension, in patients with history, symptoms or signs of ischemic heart disease, coronary artery vasospasm
, cerebrovascular or peripheral vascular disease including ischemic bowel disease and in patients with other significant underlying cardiovascular diseases or known hypersensitivity to sumatriptan.
[gamma]-Sarcoglycan mutant mice with cardiomyocyte perturbations, demonstrate coronary artery vasospasms
despite normal sarcoglycan complex in VSM.