coronary artery calcification

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Related to coronary artery calcification: coronary artery disease

coronary artery calcification

Abbreviation: CAC
Calcium phosphate (hydroxyapatite) in coronary arteries, an indicator of coronary artery atherosclerosis. CAC is found in diseased but not healthy coronary arteries. During ultrafast CT scanning of the heart, tissue densities that exceed 130 Hounsfield units typically contain significant amounts of deposited calcium. The total amount of calcium present in a person's coronary arteries can be measured by assessing the length of calcified artery and the density of the calcium identified. These factors together are used to generate a “calcium score.” A calcium score > 100 is often cited as a measurement indicative of a moderately high risk of future myocardial infarction or ischemia. People with scores > 100 should begin taking daily aspirin and should actively modify atherosclerotic risk factors such as smoking, high blood pressure, hyperlipidemia, and diabetes mellitus. A score greater than 400 is often cited as indicating an urgent need for stress testing with radionuclide imaging, e.g., thallium or sestamibi.


Caution is needed to interpret raw calcium scores. The test is not perfectly sensitive: a small number of people without coronary artery calcium deposits still may have plaque rupture and myocardial infarction. Also, the score is just one of several markers of atherosclerosis, all of which should be factored into a risk assessment for coronary artery disease.
See also: calcification
References in periodicals archive ?
Coronary artery calcification is related to coronary atherosclerosis in chronic renal disease patients: a study comparing EBCT-generated coronary artery calcium scores and coronary angiography.
The investigators also noted a high prevalence of coronary artery calcification (42.
Chest CT revealed that 870 (32%) of these women had occult coronary artery calcification, including 105 (4%) with advanced calcification.
Electron beam computed tomography and coronary artery disease: scanning for coronary artery calcification.
Major finding: The prevalence of coronary artery calcification, which indicates increased cardiovascular risk, rose steadily in accordance with the BP trajectory, from a low of 4% in group 1 patients who had a low-and-stable BP trajectory to a high of 25% in group 5 patients who a high-and-increasing BP trajectory -- even though most of these patients had BP levels within the range of "prehypertension.
Increased dietary calcium intake is not associated with coronary artery calcification.
Although association between platelets and atherosclerosis is well known (1, 21), to the best of our knowledge, there is no study demonstrating the role of platelets in evolving of coronary artery calcification.
The association between these improved lipid profiles and decreased coronary artery calcification - an underlying indicator of coronary heart disease - was confirmed using the expanded cholesterol profiling capabilities of the VAP (Vertical Auto Profile) Test.
In a study of 194 perimenopausal women from a cohort of the longitudinal, multicenter Study of Women's Health Across the Nation (SWAN), a history of recurrent depression was associated with both aortic calcification (AC) and coronary artery calcification (CAC), said Dr.
TORONTO -- Low bone mineral density in women is associated with coronary artery calcification and may be a marker for subclinical vascular disease, Dr.
provider of Nanobac proprietary blood tests that can detect blood levels of Calcifying Nanoparticles (CNPs), which are found in coronary artery calcification, kidney stones, and other stone forming diseases.

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