Also found in: Dictionary, Thesaurus, Encyclopedia.
Related to coronary arteritis: Coronary arteries
inflammation of any or all of the layers of coronary artery walls.
Farlex Partner Medical Dictionary © Farlex 2012
Kawasaki syndromeAn acute idioapathic febrile illness that primarily affects children under age 5, especially males, and has a winter-spring seasonality.
Fever; cervical lymphadenopathy; palmoplantar and mucosal erythaema and oedema; conjunctivitis; gingivitis; maculoerythematous glove-and-sock rash over the hands and feet, which becomes hard, oedematous and sloughs; aneurysms of small- and medium-sized coronary, occasionally peripheral, arteries, with arteritis. Other findings include conjunctival oedema, upper respiratory tract oedema, pharyngeal injection and truncal lymphadenopathy.
Uncertain; various bacteria have been implicated, though none definitively.
Increased ESR, CRP, complement, immunoglobulins.
Gammaglobulin in IV bolus, aspirin IV.
May cause sudden death; 1–5% die of disease.
Kawasaki syndrome case definition (CDC)
Fever of 5 days’ duration (or fever post-IV immunoglobulin if given before 5th day of fever), and 4 of following 5 signs:
• Cervical lymphadenopathy (1.5+ cm in diameter);
• Bilateral conjunctival injection;
• Oral mucosal changes—erythaema, fissuring and xerostomia, “strawberry tongue”;
• Peripheral extremity changes—e.g., acral erythema or oedema, periungual and/or generalised desquamation, polymorphous exanthematous rash.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.