cornification


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cornification

 [kor″nĭ-fĭ-ka´shun]
conversion of epithelium to the stratified squamous type.

ker·a·tin·i·za·tion

(ker'ă-tin'i-zā'shŭn),
Keratin formation or development of a horny layer; may also apply to premature formation of keratin.
Synonym(s): cornification

cornification

/cor·ni·fi·ca·tion/ (kor″nĭ-fĭ-ka´shun)
2. conversion of epithelium to the stratified squamous type.

cornification

(kôr′nə-fĭ-kā′shən)
n.
The process by which squamous epithelial cells in vertebrate animals develop into tough protective layers or structures such as hair, hooves, and the outer layer of skin; the final stage of keratinization.

cornification

[kôr′nifikā′shən]
the conversion of cells into the horny layer of the skin. Also called keratinization. cornify, v.

ker·a·tin·i·za·tion

(ker'ă-tin-ī-zā'shŭn)
Keratin formation or development of a horny layer; may also apply to premature formation of keratin.
Synonym(s): cornification.

cornification

the formation of KERATIN in the epidermis from epidermal cells, as occurs in the skin when subjected to abrasive stresses.

cornification

keratinization

ker·a·tin·i·za·tion

(ker'ă-tin-ī-zā'shŭn)
Keratin formation or development of a horny layer.
Synonym(s): cornification.

cornification (kor´nifikā´shən),

n the conversion of epithelium to a hornlike substance.
Keratinization is a more specific term. See also keratin.

cornification

1. conversion into keratin, or horn.
2. conversion of epithelium to the stratified squamous type.
References in periodicals archive ?
Williams ML, Elias PM: Enlightened therapy of the disorders of cornification.
INTRODUCTION: Ichthyosis is regarded as a disorder of keratinization or cornification and it is due to abnormal differentiation or metabolism.
Thyroid hormone is needed for initiation of anagen hair follicles, regulation of cornification process and sebaceous gland secretion (Jackson and Marsella, 2012).
Subungual hyperkeratosis is nail bed disease characterized by abnormal cornification of nail bed and hyponychium.
Among the topics are the origins and evolution of programmed cell death, caspases and cell death, mitochondrial outer membrane permeabilization, death receptors, the engulfment of apoptotic cells and its physiological roles, autophagy, regulatory genes and disease, cornification of the skin as a non-apoptotic cell death mechanism, inherited disorders, and microbial inhibitors of apopotosis.
On histologic examination, the mass was consistent with squamous cell carcinoma (SCC), based on the presence of thick, anastomosing cords of epithelial cells, with prominent irregular internal concentric cornification (Fig 3).
Chapter 6 is about the effects of retinoids on the sebaceous gland, essentially on the treatment of acne with tretinoin, tazarotene, and adapalene topically, and isotretinoin orally, with detailed consideration of irritation and other side-effects, and chapter 8 deals with retinoid treatment of disorders of cornification such as ichthyosis.
Tissue changes in mice with persistent vaginal cornification induced by early postnatal treatment with estrogen.
Expression of keratinocyte transglutaminase, TGase-1, occurs in differentiated layers of epidermal tissue and influences the cornification of the outermost layers of keratinocytes.
Calcium: Calcium is essential for keratinization and cornification process as it involves in the activation of epidermal transglutaminase which is active in cross-linkage of the cell envelope keratin fibres and in the initiation and regulation of the terminal differentiation of the epidermal cells.
5 to 1 mg/kg per day has been used for disorders of cornification and psoriasis with good results.