cornification


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cornification

 [kor″nĭ-fĭ-ka´shun]
conversion of epithelium to the stratified squamous type.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

ker·a·tin·i·za·tion

(ker'ă-tin'i-zā'shŭn),
Keratin formation or development of a horny layer; may also apply to premature formation of keratin.
Synonym(s): cornification
Farlex Partner Medical Dictionary © Farlex 2012

cornification

(kôr′nə-fĭ-kā′shən)
n.
The process by which squamous epithelial cells in vertebrate animals develop into tough protective layers or structures such as hair, hooves, and the outer layer of skin; the final stage of keratinization.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

ker·a·tin·i·za·tion

(ker'ă-tin-ī-zā'shŭn)
Keratin formation or development of a horny layer; may also apply to premature formation of keratin.
Synonym(s): cornification.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

cornification

the formation of KERATIN in the epidermis from epidermal cells, as occurs in the skin when subjected to abrasive stresses.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005

ker·a·tin·i·za·tion

(ker'ă-tin-ī-zā'shŭn)
Keratin formation or development of a horny layer.
Synonym(s): cornification.
Medical Dictionary for the Dental Professions © Farlex 2012
References in periodicals archive ?
Furthermore, the alkaloids did not provoke vaginal opening or cornification in any of the animals (Table 3).
Evaluation of the estrogenic activity of the wild Pueraria mirifica by vaginal cornification assay.
of California, San Francisco, and Innsbruck Medical U., Austria) explain the ultrastructure, clinical features, biochemical genetics, and cellular pathogenesis of monogenic inherited disorders of cornification. They consider the disease pathogenesis from functional abnormalities to the responsible gene and discuss inherited disorders of lipid metabolism, accelerated desquamation, and corneocyte proteins.
(72) DHEA "switched on" multiple collagen-producing genes and reduced expression of genes associated with production and cornification (hardening) of the tough keratinocytes that form calluses and rough skin.
In metastatic tumors from squamous carcinoma, cavitation might result from cornification of the squamous epithelium in the center of the lesion with subsequent liquefaction and evacuation into airway.
Also, our findings of the vaginal smears obtained from group II showed pro-estrous smears which were characterized by rounded, usually nucleated, epithelial cells, generally in low to moderate numbers and even some epithelial cells show early stages of cornification. Both these histological and cytological features were not detected in the groups that received normal saline (Group III) or the group that received nothing (Group IV).
Neoplastic cells were cuboidal to polygonal, with variable degrees of squamous differentiation and cornification toward the center of nests.
Cluster analysis of the data showed that RA suppressed protein markers of cornification, biosynthesis of epidermal lipids, long chain fatty acids, cholesterol and sphingolipids.
This layer is constantly abraded by chemical and physical agents and renewed by a very slow process of cornification, which transforms keratinocytes into corneocytes.
Squamous differentiation was universal, with all tumors exhibiting cytoplasmic cornification and 41% having keratinizing cysts.
Keratinocyte transglutaminase (TGasel) is a well-documented protein which appears in differentiated layers of epidermal tissue and influences the cornification of the outermost layers of keratinocytes.