corneal sensitivity

sensitivity, corneal 

The capability of the cornea to respond to stimulation. Corneal sensitivity to touch is assessed by an aesthesiometer that measures the corneal touch threshold (CTT), which is the reciprocal of corneal sensitivity. Sensitivity varies across the cornea, with the centre being the most sensitive. Diseases and rigid contact lens wear greatly reduce the sensitivity of the cornea. See aesthesiometer; corneal touch threshold; corneal hyperaesthesia.
References in periodicals archive ?
The cornea is the most densely innervated tissue in the body, and this innervation provides corneal sensitivity. Many diseases disrupt corneal sensitivity, including ocular infections, herpetic eye disease, dry eye syndrome, and diabetes.
In this study, we found that corneal sensitivity was significantly decreased in untreated diabetic rats, diabetic rats treated with salsalate alone, diabetic rats treated with 10% menhaden oil with or without salsalate, and diabetic rats treated with 25% menhaden oil compared to control rats (Table 2).
The patient did not experience any eye pain and corneal sensitivity measured with Cochet-Bonnet esthesiometer was <10 mm in the right eye and 60 mm in the left, showing remarkable decline of corneal sensitivity in the right.
Animal experimental studies revealed that topical application of NGF accelerated restoration of corneal sensitivity and promoted cornea epithelial proliferation and nerve regeneration after laser in situ keratomileusis (LASIK) or photorefractive keratectomy (PRK) [85-87].
The corneal sensitivity, number of corneal nerve fibers, and contents of vascular endothelial growth factor (VEGF)-B and various neurotrophic factors such as nerve growth factor (NGF) and glial cell line-derived neurotrophic factor (GDNF) in corneal tissue of four groups were observed.
Multiple studies have revealed the influence of diclofenac and ketorolac in fading pain along with corneal sensitivity consequent to corneal abrasion.4
Corneal sensitivity has alert function for possible injuries or diseases (BROOKS et al., 2000).
However, the microkeratome operated eyes showed significantly higher incidence of dry eyes than femto-LASIK operated eyes (p 0.05), but VisuMax offered faster recovery of corneal sensitivity and tearfilm break-up time.26
Impairment of corneal sensitivity results in diminished blink and lacrimal reflexes.
Chronic corneal ulceration, entropion, decreased corneal sensitivity and some infectious agents like feline herpes virus-1 have been considered as triggering factors in formation of corneal sequestrum (Williams and Kim, 2009).
The effects of the topical administration of non-steroidal anti-inflammatory drugs on corneal epithelium and corneal sensitivity in normal subjects.