CORIN(redirected from corin, serine protease)
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CORINA gene on chromosome 4p13-p12 that encodes a serine-type endopeptidase which converts non-functional propeptide NPPA into active atrial natriuretic peptide hormone, resulting in natriuresis, diuresis and vasodilation. CORIN may also process pro-NPPB, the B-type natriuretic peptide.
Defects in CORIN cause pre-eclampsia/eclampsia type 5.
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