convulsant

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con·vul·sant

(kon-vŭl'sant),
A substance that produces convulsions.
See also: eclamptogenic, epileptogenic.
Farlex Partner Medical Dictionary © Farlex 2012

convulsant

(kən-vŭl′sənt)
adj.
Causing or producing convulsions.
n.
An agent, such as a drug, that causes convulsions.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

convulsant

(kŏn-vŭl′sănt) [L. convellere, to pull together]
1. An agent that produces a convulsion.
2. Causing the onset of a convulsion.
Medical Dictionary, © 2009 Farlex and Partners

Patient discussion about convulsant

Q. my friend has convulsions what can i do to make it stop and improve his life quality?

A. what type of convulsions? my best friend is epileptic, but as long as he get's his meds and sleep well- nothing ever happens. i know that as a child all my friend ever wanted was to go to school like everyone else... and to go to school trips without being afraid.

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References in periodicals archive ?
Polyunsaturated fatty acids modify mouse hippocampal neuronal excitability during excitotoxic or convulsant stimulation.
Mapping convulsants' binding to the GABA-A receptor chloride ionophore: a proposed model for channel binding sites.
METHODS AND RESULTS: By screening the affinity of RDX for a number of neurotransmitter receptors, we found that RDX binds exclusively to the picrotoxin convulsant site of the [gamma]-aminobutyric acid type A ([GABA.sub.A]) ionophore.
CONCLUSIONS: These results suggest that binding to the [GABA.sub.A] receptor convulsant site is the primary mechanism of seizure induction by RDX and that reduction of GABAergic inhibitory transmission in the amygdala is involved in the generation of RDX-induced seizures.
Here, we present evidence that RDX binds at the convulsant site of the [gamma]-aminobutyric acid type A ([GABA.sub.A]) receptor (Benarroch 2007; Johnston 2005; Kalueff 2007), causing reduction of [GABA.sub.A] receptor-mediated synaptic transmission and induction of epileptiform activity, as we demonstrate in the amygdala, a seizure-prone structure of the limbic system (Aroniadou-Anderjaska et al.
Key words: Nantenine, Aporphine, Alkaloid, Anticonvulsant activity, Convulsant activity
The convulsant activity previously observed at high doses was also investigated.
(i.p) (a dose previously determined as 100% convulsant).
Fisher's exact test was performed to determine significance of other anticonvulsant and convulsant properties results.
At 7 days postfertilization (dpf), after having undergone completion of brain formation at 5 dpf, zebrafish exhibit behavioral, electro-graphic, and molecular changes to chemical convulsants that would be expected from a rodent seizure model.
p,p '-DDE exposure of zebrafish embryos increases sensitivity of the fish to chemical convulsants. Our previous experiments indicated that this effect was apparent at bath exposure levels as low as 0.3 [micro]M p,p '-DDE (Tiedeken and Ramsdell 2009).
After brain maturation (7 days postfertilization), fish were exposed to a chemical convulsant, either pentylenetetrazole or domoic acid; resulting seizure behavior was then monitored and analyzed for changes, using cameras and behavioral tracking software.