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A gene on chromosome 22q11.1, which encodes a member of the BCL-2 family of cell death regulators. BID heterodimerises with either agonist BAX or antagonist BCL2. Caspase-8 cleaves BID, mediating mitochondrial damage when the COOH-terminal part translocates to mitochondria, triggering cytochrome c release.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

bis in di·e

, bid (bis in dē'ā)
Twice a day.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012


Abbreviation for bis in die.
Medical Dictionary for the Dental Professions © Farlex 2012
References in periodicals archive ?
Upon receipt of the contractor's proposal, the program's technical evaluator performs a preliminary review of the proposal to ensure at least the following recommended compliances:
(4) The contractor's proposal contains adequate description of its basis for direct labor hours, including sufficient rational for engineering judgment and projections from prior work completed on similar programs;
(6) The contractor's proposal provides supporting data to justify proposed material, scrap, rework, attrition, or other factors; and
The failure to provide a comprehensive technical analysis of a contractor's proposal can seriously delay the award of the contract action, impede an effective price analysis, extend negotiations, and cause difficulties in contract performance after award.
By keeping a strict adherence to organization of the technical assessment consistent with the contractor's proposal, the technical evaluation will assist the price analyst and negotiator in establishing a reasonable position, based on factual, measurable, and easily recognizable differences in the contractor's proposal and the technical assessment.
A primer for organizing a technical evaluation consists of starting with a summary paragraph briefly describing the work proposed and any unique aspects to the contractor's proposal. The technical evaluation should then summarize the proposed hours with clarity, traceability, and completeness.
The basis for understanding and producing a cohesive technical evaluation is: (a) reading and understanding the Statement of Work (SOW) and the contractor's cost and technical proposal, Co) reviewing the scope of the tasks proposed by the contractor, (c) reviewing the contractor's estimating methodologies and rationale, (d) evaluating the detailed estimates, calculations, and factor applications used in the contractor's proposal, and (e) formulating a technical analysis plan after evaluating all the detailed estimates.
If additional information is required to understand the contractor's cost and technical proposal, the program's technical evaluator should contact the contracting officer to request better insight into the contractor's proposal. As a result, a series of fact-finding meetings may be necessary to resolve any issues and gain a full understanding of what the contractor is proposing for the contract.

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