contortrostatin

contortrostatin

(kon-tōr'trō-stat'in),
A monomeric disintegrin (q.v.) isolated from crotalid venom.
[fr. Agkistrodon contortrix, species of source viper, + G. istēmi, to check, arrest, + -in]

contortrostatin

(kŏn-tŏr″trō′stă′tĭn) [NL. contortrix (Southern) copperhead +statin]
A protein derived from snake venom that inhibits the migration of cells (e.g., of metastasizing cancer cells).
References in periodicals archive ?
Snake venom is deadly but is being used to treat some cancers, (1) because it produces contortrostatin, a protein that "paralyzes" cancer cells and prevents them from migrating.
Contortrostatin, a disintegrin from Agkistrodon contortrix contortrix venom, is an example of an effective inhibitor of [[beta].sub.1]-integrin-mediated adhesion in metastatic melanoma cells [30].
The protein, called contortrostatin, or CN, does not kill tumour cells but "freezes" them in a long lasting state of suspended animation.
The protein, called contortrostatin or CN, does not kill tumour cells but "freezes" them.