contiguous gene syndrome
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contiguous gene syndromeA nonspecific term for any clinical syndrome which is caused by the loss, alteration or mutation of two or more genes that are adjacent to each other on the same chromosome, as occurs in deletion.
Prader-Willi—microdeletion of 15q11-13; WAGR syndrome—deletion of 11p13.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
contiguous gene syndromeA syndrome featuring a range of apparently unrelated clinical defects that are actually due to deletion of a length of DNA containing adjacent genes the loss of each of which causes a specific defect.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005