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2. In genetics, descriptive of a gene that is controlled by constantly active promoter.


/con·sti·tu·tive/ (kon-stich´u-tiv) produced constantly or in fixed amounts, regardless of environmental conditions or demand.


(kŏn′stĭ-to͞o′tĭv, -tyo͞o′-)
1. Making a thing what it is; essential.
2. Of or relating to the synthesis of a protein or an enzyme at a constant rate regardless of physiological demand or the concentration of a substrate.

con′sti·tu′tive·ly adv.


produced at a steady rate, independent of internal or external stimuli. Said of enzymes, RNA or protein by an organism.

Patient discussion about constitutive

Q. What really constitutes ADD? Don't all kids have short attention spans because they are curious? What I'm saying is. I'm a very curious fellow, so, therefore, I cannot hold my attention to one thing for more than a minute. Does this mean I have ADD?

A. to what you said about how come they didn't have all these problems lots of years ago, I'll have to say it is true the kids today have a lot more stimulations than what kids had a 100 years ago, though, these problems- ADD and ADHD did exist, even with less things around to lose focus to. even about 20 years ago, when the awareness was too small, teachers just called these kids "stupid" or slow, cause they wern't able to listen for a long period of time and then did'nt know what to answer when asked. the awareness helped save lots of very smart focusless kids...

More discussions about constitutive
References in periodicals archive ?
Blockade of constitutively activated Janus kinase/signal transducer and activator of transcription-3 pathway inhibits growth of human pancreatic cancer.
Because the XBP1 intron removed by this splicing is only 26 nucleotide' long, it cannot block translation, and therefore XBP1 precursor mRNA is constitutively translated to produce pXBP1(U), which functions as a negative regulator of pXBP1(S).
That is why 'the transition from Newton to Einstein centrally involves a succession of relativized constitutively a priori principles (the Newtonian Laws of Motion in the context of the Principia, in the light principle and the principle of relativity in the context of special relativity, the light principle and the principle of equivalence in the context of general relativity), and the existence of such diverse constitutively a priori principles, on my view, captures the essence of Kuhnian incommensurability' (713-14).
For evaluation of phosphorylated 4E-BP1, we used an antibody that detects phosphorylation at Thr37/46 because (1) phosphorylation on these residues by mammalian target of rapamycin or other upstream pathways is a prerequisite for subsequent hyperphosphorylation at Thr70 and Ser65 as well as for blocking binding to eIF4-E22 and (2) we showed that mutation at Thr37/46 creates a 4E-BP1 form that is constitutively functionally active and inhibits tumorigenesis.
Historically, the university has been "the only institution that is constitutively committed to enlightenment," that is, to bringing the heritage of critical thought to bear on issues of public concern.
If representation is constitutively inadequate for our experience of the world and of others, as Levinas suggests, at the same time Borges's writing leaves us with the knowledge that there is no such thing as a complete escape from representation (except, perhaps, in psychosis).
Studies performed on monolayers of cultured endothelial cells have revealed that ICAM-1 and, to a lesser extent, VCAM-1 are both constitutively expressed on these cells [28,29].
10) On Soldati's reading, Brentano introduces the idea of mental phenomena as being constitutively intentional, necessarily directed onto an object.
This is a problem for Dharmakirti insofar as (a) the exercise of our conceptual capacities--which constitutively involve normative relations such as (in the words of philosopher John McDowell) "one thing's being warranted or correct in light of another" (4)--do not very readily admit of causal explanation; and (b) the constitutively non-conceptual (kalpanapodha) character of perception consists, for Dharmakirti, precisely in its being causally describable.
Schestag presents a constitutively broken word that produces transience, difference, and transformation within seemingly permanent things.
In academic essays on modern Islamic thought, two Islamist academics, Suha Taji-Farouki and Bashir M Nafi, observe: "Rather than being a development within cultural traditions that is internally generated, 20th-century Islamic thought is constitutively responsive; it is substantially a reaction to extrinsic challenges".