consolidation chemotherapy


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Related to consolidation chemotherapy: induction chemotherapy, salvage chemotherapy, platinum chemotherapy

con·sol·i·da·tion che·mo·ther·a·py

repetitive cycles of treatment during the immediate postremission period, used especially with relation to leukemia.

consolidation chemotherapy

Consolidation treatment Oncology A phase of chemotherapy–CT intended to liquidate residual malignant cells in Pts with leukemia or other lymphoproliferative malignancies in remission; CC follows 'intensification' phase of CT, which in turn is followed by a maintenance phase. Cf Adjuvant chemotherapy, Induction chemotherapy, Intensification chemotherapy, Maintenance chemotherapy, Salvage chemotherapy.

consolidation chemotherapy

A cycle of therapy with cytotoxic drugs after the initial treatment for a cancer. The object is to sustain a remission achieved during induction.
See also: chemotherapy
References in periodicals archive ?
Such a risk is the highest in non-selective application of SCT after finishing consolidation chemotherapy. Some thirty years ago, the EBMT group [62] published data that LFS, patient mortality and risk of relapse are 23%, 13% and 64% if auto-SCT is applied in the first three months of first remission of AML, and that the same parameters are 48%, 6% and 46% if auto-SCT is applied after six months of remission.
It is questionable whether primary Posaconazole prophylaxis would have been able to prevent the Aspergillus infection, allowing for timely consolidation chemotherapy. However, it is known that Posaconazole prophylaxis reduces the incidence of invasive fungal disease from 8% to 2% in high risk AML and myelodysplastic syndrome patients [9-11].
Different practitioners or institutions have varied standards of protocols, with induction chemotherapy before concurrent chemo-RT preferred by some,[sup][4] and others practicing consolidation chemotherapy after concurrent chemo-RT.[sup][5] As far as recommended systemic treatment for stage 3 NSCLC is concerned, it comprises 2–4 cycles of chemotherapy.
Background: The postremission therapies for adult patients generally contain consolidation chemotherapy, allogeneic hematopoietic stem cell transplantation and autologous hematopoietic stem cell transplantation (auto-HSCT).
All patients had received prior therapy consisting of induction combination chemotherapy, maximum feasible surgical resection, myeloablative consolidation chemotherapy followed by autologous stem cell transplant and radiation therapy to residual soft tissue disease, concluded the company.
The patient is currently in remission and is being monitored in the course of allogeneic hematopoietic stem cell transplantation to follow consolidation chemotherapy.
After induction, patients could receive up to four cycles of consolidation chemotherapy while continuing ivosidenib or enasidenib.

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