Although the formation of typical A-type inclusions is restricted to cells infected with cowpox virus, ectromelia virus, and raccoonpox virus (2), the sequence coding the N-terminus of the protein is highly conserved in many viruses, including CPXV, VACV, variola virus, camelpox virus, and ectromelia virus.
Through a monetary valuation of the economic benefits that conserved lands provide, the results of this project are intended to more clearly articulate the value of Texas conservation lands and open spaces to decision makers.
This is partly due to the amount of work required to construct conserved flows; it can be cumbersome and tedious when dealing with the large systems of differential equations that arise in physics, cosmology, and engineering.
Since amino acid residues that are vital for function or structural stability of a protein tend to be conserved across species, any differences at the functional sites would indicate possible differences for biological activity.
In different laboratory tests, Quadvax-induced antibodies inhibited the growth of 26 different parasite strains, and the scientists suggest that "the combination of four AMA1 variants in Quadvax may be sufficient to overcome global AMA1 diversity." Besides varying a lot from strain to strain, AMA1 also contains less variable (conserved) exposed parts (so-called epitopes) on its surface.