consensus sequence


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consensus sequence

[kənsen′səs]
a sequence of nucleotides or amino acids similar or identical between regions of homology in different but related DNA, RNA, or protein sequence.

consensus sequence

a sequence of NUCLEOTIDES or AMINO ACIDS that is used to describe a number of related but not identical sequences. It is compiled by inserting the nucleotide occurring most often at each position in the real sequences.

sequence

the order in which monomers occur in polymeric molecules; the order of amino acids in a polypeptide chain or of nucleotides in nucleic acid.

autonomously replicating sequence
usually plasmids that replicate independently of chromosomal DNA.
coding s's
sections of DNA which code for the amino acids of a protein.
consensus sequence
a sequence of nucleotides that is always present in a large set of independently determined sequences. See also box.
enhancer sequence
in DNA transcription, an upstream cis-acting DNA sequence that enhances expression of a particular gene and forms part of a complex array of upstream sequences that control gene expression.
expressed s's
in eukaryotic pre-messenger RNA the noncoding sequences, also called intervening sequences or introns, are removed in the nucleus; the mRNA is transported to the cytoplasm where the exons are translated to a protein.
intervening sequence
see intron.
palindromic sequence
signal sequence
a collection of hydrophobic amino acid residues at the amino terminus of secretory or integrated membrane proteins that direct the protein to cell membranes, particularly endoplasmic reticulum where the proteins are modified, e.g. glycosylated, and the signal sequence is removed prior to secretion or integration of the protein into the lumen of the endoplasmic reticulum.
temporal sequence
in protein synthesis, is from the amino to the carboxyl end.
References in periodicals archive ?
HLA genotyping results and fully phased consensus sequences were successfully generated for all 50 participants using the Omixon Twin algorithm (300 total alleles) and were found to be concordant with SBT/SSP genotyping results (2 field resolution, data not shown).
1 In bold the restriction site for Kpnl, in italic the lexA box consensus sequence, underlined the [bla.
Three sera that showed HBV DNAs identical to consensus sequences from genotypes A, D and F, were selected for plasmid construction.
Four Chinese hamster (Cricetulus griseus) loci were chosen which contained a B2 element that demonstrated high sequence identity to the consensus sequence.
The consensus sequence of plant MYB-binding domain has been found in promoters of flavonoid biosynthetic genes such as phenylalanine ammonia lyase, chalcone synthase, and dihydroflavonol 4-reductase (Sablowski et al.
The closest matches (98% identity) were to sequences from CCAP strains 1560/4 and 1560/5, the sequences most closely related to the consensus sequence from 2001 to 2002 lobsters (Fig.
Then, at each of these sites, both taxa are compared with the consensus sequence.
Newcastle disease strains of NDV of different genotypes have functional domains of F and HN proteins with consensus sequences that recognized several amino acid substitutions.
For example, the first ZF (ZF1) domain binds GA(CT)AAGATAAGATAA-containing sequence, (27) and it also binds the promoter region of GATA2, thus activating GATA2 activity28; ZF2 domain binds DNA with consensus sequence as GACAAGATAATATAAN1-28 CTCATCTTC.
This is a structure that comprises 5 amino acid residues having a consensus sequence of "Gly-X- Ser-Y-Gly" (Derewenda and Derewenda, 1991).
Analysis of both BLAST and BOLD confirmed that the consensus sequence (KF472312) generated from this insect was in the superfamily Fulgoroidea; however, no significant match could be made below this taxonomic level.
Whole-genome sequencing generates a single consensus sequence without assigning variants to specific homologous chromosomes.