Extracellular loops are highly conserved which consists of three cysteine residues mainly responsible for proper alignment of connexons between adjacent cells (19).
Each connexon comprises six connexins which are assembled in the endoplasmic reticulum or in the Golgi apparatus to form a connexon hemi-channel.
In the present study, we used the two-electrode voltage-clamp recording technique to examine the effects of zinc on the currents mediated by the connexons
formed by the endogenous connexin (Cx38) of stage V-VI Xenopus oocytes, and those formed by perch Cx35, a connexin expressed in neurons of the vertebrate retina (11, 12).
To characterize the hemichannel activity of connexons
, non-junctional current recordings were obtained from single oocytes with a two-electrode voltage-clamp procedure.
Given that the latter appear to express the [Beta]2-like adrenoceptors associated with luminescence control (Awad and Anctil, 1993, 1994), the likelihood is great that intercellular coupling involving Cx43-related connexons participates in downstream transmission of signals to the photocytes themselves.
Possible ultrastructural substrates of junctions involving connexons
1984), "the failure to observe gap junctions in these groups could merely mean that the junctions are very small, consisting of isolated connexons, or small groups of them.
comprises a pairs of Connexin43, 46 and 50 subunits (Santana and Waiswo, 2011; Beyer and Berthoud, 2014).
is a hexagonal arrangement of six subunits of a protein named connexin (Cx).