connexons


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con·nex·ons

(kŏ-neks'ŏnz),
Complex protein assemblies that traverse the lipid bilayer of the plasma membrane and form a continuous channel with a pore diameter of approximately 1.5 nm; a pair of connexons from two adjacent cells join to form a gap junction that bridges the 2-4-nm gap between the cells, resulting in both electrical and metabolic couplings; one type of connexons makes up the gap junction in the heart and may coordinate the beating of all muscle cells in one section of the heart.
See also: connexins.

connexons

components of the gap junction spaces between nerve cells; metabolic substances pass between nerve cells via these links.
References in periodicals archive ?
Extracellular loops are highly conserved which consists of three cysteine residues mainly responsible for proper alignment of connexons between adjacent cells (19).
Each connexon comprises six connexins which are assembled in the endoplasmic reticulum or in the Golgi apparatus to form a connexon hemi-channel.
Small intracellular pores in endothelial cells may also open in the presence of 5-HT Cx43 is a major connexin found in endothelial cells and is found in connexons, transmembrane gap junctions that allow the diffusion of small molecules between cells.