connexon


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connexon

(kŏn-ĕks′ŭn)
A protein that forms tunnels across gap junctions, enabling ions or small molecules, such as glucose, to pass from one cell to another.
References in periodicals archive ?
About 911 Enable 911 Enable, a division of Connexon Telecom Inc., is the industry-leading provider of E911 solutions for IP telephony systems, having deployed its solutions in organizations of all sizes across the US and Canada, including Fortune 500 companies.
Gating is a reversible transition between connexon channel due to the result of non covalent and covalent modifications of the channel structure.
Six connexin (Cx) subunits oligomerize into connexon, which is called a hemichannel after insertion into plasma membrane.
This complex is called a connexon and constitutes a hemichannel [59].
Six connexin polypeptides oligomerize to form a membrane hemichannel, or connexon, which can dock with the connexons from adjacent cells to form an aqueous pore (d [approximately equal to] 16 A) which allows the cell-to-cell diffusion of ions, second-messenger molecules, and metabolites having a molecular mass [less than or equal to] 1 kDa.
Six connexin polypeptides oligomerize to form a membrane hemichannel or connexon, clusters of which join with the connexons of adjacent cells to create the gap junction.
These agents are known for their blocking effect on coupling via gap junctions (Johnston et al., 1980; Turin and Warner, 1980; Spray et al., 1982) and have perturbing effects on the ultrastructure of connexon arrangements (Deleze and Herve, 1983).
GJs are made by docking of two hexameric hemichannels (connexons) of two apposed cells, thus composed of 12 proteins called connexins.
Dermietzel, "Connexons and cell adhesion: a romantic phase," Histochemistry and Cell Biology, vol.
Pannexin1 and Pannexin2 channels show quaternary similarities to connexons and different oligomerization numbers from each other.
Gap junctions, made up of connexons; sustain the integral function of cells by permitting communication between them.
The gap junctions (GJs) are hemichannels, called connexons, each formed by six connexins.