GJC2

(redirected from connexin-47)

GJC2

A gene on chromosome 6q15-q18 that encodes a gamma chain of the gap junction protein family or connexins, which is required for central
myelination and is involved in peripheral myelination.

Molecular pathology
GJC2 mutations are linked to autosomal recessive Pelizaeus-Merzbacher-like disease-1.
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References in periodicals archive ?
Morita et al., "Connexin-47 and connexin-32 in gap junctions of oligodendrocyte somata, myelin sheaths, paranodal loops and Schmidt-Lanterman incisures: implications for ionic homeostasis and potassium siphoning," Neuroscience, vol.