conjugate

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conjugate

 [kon´joo͡-gāt]
1. paired, or equally coupled; working in union.
2. a conjugate diameter of the pelvic inlet, especially the true conjugate diameter; see pelvic diameter.

con·ju·gate

(kon'jŭ-gāt), [TA]
1. Joined or paired. Synonym(s): conjugated
2. Conjugate diameters of the pelvis. The distance between any two specified points on the periphery of the pelvic canal.
[L. conjugatus, joined together. See conjugata]

conjugate

(kŏn′jə-gāt′)
v. conju·gated, conju·gating, conju·gates
v.tr.
To join together.
v.intr.
Biology To undergo conjugation.
adj. (-gĭt, -gāt′)
1. Joined together, especially in a pair or pairs; coupled.
2. Chemistry Conjugated.
n. (-gĭt, -gāt′)
Chemistry A chemical compound that has been formed by the joining of two or more compounds.

con′ju·gate′ly adv.
con′ju·ga′tive adj.
con′ju·ga′tor n.

con·ju·gate

(kon'jŭ-găt) [TA]
1. Joined or paired.
Synonym(s): conjugated.
2. A conjugate diameter of the pelvis. The distance between any two specified points on the periphery of the pelvic canal.
See: conjugata
[L. conjugatus, joined together]

conjugate

Coupled or joined in pairs or groups. Of co-valently linked complexes of two or more molecules.

con·ju·gate

(kon'jŭ-găt) [TA]
Joined or paired, conjugated.
[L. conjugatus, joined together]
References in periodicals archive ?
The HPC-Ibuprofen conjugates 1-3 were characterized with the help of spectroscopic and chromatographic analyses.
We describe for the first time the use of ADH as a linking reagent between glycoenzyme (HRP) and a steroid carboxylic derivative to prepare enzyme conjugate for ELISA.
Flat-bottomed 96-well polystyrene immunoplates (NUNC, Maxisorp; Nalge NUNC, Rochester, NY) were coated with 100 [micro]L of PbTx-3-bovine serum albumin (BSA) conjugate (24,29,30) (250 ng/mL) or BSA alone by incubating for 1 hr at 25 [degrees] C or overnight at 4 [degrees] C in PBS.
Starpharma's HER-2 Targeted DEP conjugate in this experiment consisted of a dendrimer scaffold, a targeting group (in this case a novel HER-2 targeted antibody fragment) and a 'payload' of anti-cancer drug.
Meanwhile, it also provides a wide range of services through all stages of drug R&D to support the pharmaceutical industry, like custom synthesis of chemicals, isotope labeling, formulation service, antibody drug conjugates, chiral synthesis and resolution.
- Madrid, Spain-based oncology-focused PharmaMar (MCE: PHM) has released positive results of MI130004, a novel antibody conjugate combining trastuzumab with PM050489, a molecule of marine origin, the company said.
Successful clinical translation of antibody-drug conjugates (ADCs) can be challenging due to complex pharmacokinetics and differences between preclinical and clinical tumors.
AbbVie also receives exclusive worldwide rights to develop and commercialize Probody drug conjugates against as many as two additional, undisclosed targets and CytomX would be eligible to receive additional milestone and royalty payments.
The antigenic component in conjugates was verified through a WB for which, conjugates separated on SDS-PAGE were actively transferred onto a PVDF membrane (Pierce) for 80 min at 65 mA.
Testing of Conjugates: The conjugate was tested by Immunohistochemical staining (Direct method).
Summary: Macromolecular prodrugs (MPDs) of mefenamic acid were designed onto a cellulose ether derivative hydroxypropylcellulose (HPC) as ester conjugates. Fabrication of HPC-mefenamic acid conjugates was achieved by using p-toluenesulfonyl chloride as carboxylic acid (a functional group in drug) activator at 80C for 24 h under nitrogen atmosphere.