conjugated linoleic acid


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conjugated linoleic acid

Abbreviation: CLA
Any of the isomers of linoleic acid effective against cancer, obesity, diabetes, and atheromata in laboratory rodents. CLAs have not been shown to have similar beneficial effects in humans.
See also: acid
References in periodicals archive ?
Cumulative effects of conjugated linoleic acid and exercise on endurance development, body composition, serum leptin and insulin levels.
Chen, "Oxidative stability of conjugated linoleic acid isomers," Journal of Agricultural and Food Chemistry, vol.
The major intermediates of the BH of polyunsaturated fatty acids (PUFA) by rumen bacteria are conjugated linoleic acids (cis9, trans11 C18:2; CLA) and trans-vaccenic acid (trans11 C18:1; TVA).
Kennelly, "Effect of conjugated linoleic acid on bovine mammary cell growth, apoptosis and stearoyl Co-A desaturase gene expression," Domestic Animal Endocrinology, vol.
Trans-10, cis-12 conjugated linoleic acid causes inflammation and delipidation of white adipose tissue in mice: a microarray and histological analysis.
Biosynthesis of conjugated linoleic acid in ruminants and humans.
Vegetable oil supplementation reduced linoleic acid to 76%, palmitoleic 23%, and heptadecanoic 35% compared to unsupplemented control group (Table 2), although there was an increase in undecylic, myristoleic, and conjugated linoleic acids (CLA) up to 70% respect the fat milk content (Table 2).
McLeod, "Conjugated linoleic acid isomers have no effect on atherosclerosis and adverse effects on lipoprotein and liver lipid metabolism in [apoE.sup.-/-] mice fed a high-cholesterol diet," Atherosclerosis, vol.
Conjugated linoleic acid (CLA) term includes several isomers of linoleic acid, with two main isomers: cis9,trans11 (80-90% of total CLA) and trans10, cis12.
[20] showed that a diet supplemented with conjugated linoleic acid decreased body weight in mice and enhanced fatty acid [beta]-oxidation, supported by increased carnitine palmitoyltransferase activity in the skeletal muscle and fat pad, and also that linoleic acid reduced lipoprotein lipase activity while apparently enhancing lipolysis in a study of 3T3-L1 adipocytes treated with conjugated linoleic acid.