conjugated bilirubin


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Related to conjugated bilirubin: Unconjugated bilirubin

di·rect re·act·ing bil·i·ru·bin

the fraction of serum bilirubin which has been conjugated with glucuronic acid in the liver cell to form bilirubin diglucuronide; so called because it reacts directly with the Ehrlich diazo reagent; increased levels are found in hepatobiliary diseases, especially of the obstructive variety.

conjugated bilirubin

Direct bilirubin Bilirubin chemically bound to a glucuronide in the liver, which is excreted in bile by the liver and stored in the gallbladder or transferred to the duodenum Ref range Direct BR: 0–0.3 mg/dL ↑ in Bile duct obstruction, cirrhosis, Crigler-Najjar syndrome, Dubin-Johnson syndrome, hepatitis. See Bilirubin.
References in periodicals archive ?
Serum from a patient without myeloma and a comparable concentration of conjugated bilirubin was included as a control.
Abbreviations T2DM: Type 2 diabetes mellitus BMI: Body mass index SBP: Systolic blood pressure DBP: Diastolic blood pressure DPN: Diabetic peripheral neuropathy WHR: Waist-hip ratio HbA1c: Glycated hemoglobin LDL-C: Low-density lipoprotein cholesterol HDL-C: High-density lipoprotein cholesterol CHO: Cholesterol TG: Triglyceride ALT: Alanine aminotransferase AST: Aspartate aminotransferase TBil: Total bilirubin CBil: Conjugated bilirubin UCBil: Unconjugated bilirubin NSS: Neuropathy symptom score NDS: Neuropathy disability score MNSI: Michigan Neuropathy Screening Instrument ESC: Electrochemical skin conductance.
From 556 patients, 96.6% had a normal pH value (4.8 to 7.4) and 19 (3.4%) had a basic pH ([greater than or equal to]7.4); these patients with a basic urinary pH had significantly lower serum values of BUN, TB, conjugated bilirubin [DB], and unconjugated bilirubin [IB] (Table 3) and a significant lower frequency of hepatic dysfunction (OR 0.6, CI 0.5-0.8) (Table 4).
Cholestasis results from reduced excretion of bile due to a number of disorders [1] and is defined as conjugated bilirubin more than 20% of the total bilirubin when the total bilirubin is 85 [micro]mol/L or more, and 17 [micro]mol/L or more when the total bilirubin is 85 [micro]mol/L or less.
In relation to the test performed to evaluate the ability of the active in reducing bilirubin accumulation, 0.01% conjugated bilirubin was mixed with 10mg/mL plankton extract for 24 hours.
Synthetic conjugated bilirubin (ditaurobilirubin, Lee Biosolutions, St Louis, Missouri) was dissolved in phosphate-buffered saline, pH 7.4 (final concentration 300 mg/dL), aliquoted, and frozen at -80[degrees]C.
Six months after discontinuation of lisinopril ALP was 199 U/L, GGT 168 U/L with AST 19 U/L, ALT 17 U/L, total bilirubin 0.9mg/dl and conjugated bilirubin 0.21mg/dl.
To investigate the impact of 2,5-HD treatment on liver function, the levels of AST, ALT, ALP, albumin, and total and conjugated bilirubin were determined in the serum of control and 2,5-HD-treated rats after 21 days.
Raised levels of bilirubin * Conjugated Bilirubin. Water soluble (needs to be in this state for excretion) * Unconjugated Bilirubin.
Each step in the metabolism of haeme to conjugated bilirubin involves enzymes.
Because conjugated bilirubin does not cross the placenta from the fetal into the maternal circulation, it is excreted into the fetal bile or amniotic fluid, where it is then transferred to the maternal circulation.
PN-related cholestasis was defined as an elevation of conjugated bilirubin greater than or equal to 50 [micro]mol/L subsequent to initiation of PN.