conglutinin


Also found in: Encyclopedia, Wikipedia.

conglutinin

 [kәn-gloo´tĭ-nin]
a nonimmunoglobulin bovine serum protein that aggregates immune complexes with conglutinogen activity (inactivated C3b) in the presence of divalent cations. It has been used as an indicator system, replacing complement fixation, in serologic tests, and in the detection of immune complexes. Not to be confused with immunoconglutinin.
immune conglutinin immunoconglutinin.

con·glu·ti·nin

(kon-glū'ti-nin),
Bovine serum protein that, when absorbed by erythrocyte-antibody-complement complexes, causes them to agglutinate; it is comparatively thermostable and apparently dissociates when diluted with physiologic saline solution.
Synonym(s): bovine colloid
References in periodicals archive ?
Suzuki et al., "Anti-influenza A virus activities of mannan-binding lectins and bovine conglutinin," Journal of Veterinary Medical Science, vol.
The assays that are used routinely in clinical laboratories are based on (a) precipitation of CICs by polyethylene glycol, (b) interaction of CICs with complement (C1q assay), (c) detection of CICs bound to C3 (Raji cell assay, conglutinin assay), and (d) binding of CICs to Fc-recognizing molecules (mRF assay).
Unexpected possibilities for the use of conglutinin binding assay in inflammatory rheumatic diseases.