conformer


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con·form·er

(kon-fōr'mer),
1. A mold, usually of plastic material, used in surgical repair to maintain volume in a cavity or to prevent closing of a reconstructed artificial or natural space.
2. a prion protein conformation; abnormal configuration of abnormal prion protein (that is, conformers) can induce change in the secondary and tertiary structure of normal prion protein to generate additional amounts of the abnormal protein.
[L. conformo, to fashion]

conformer

A mould placed in a cavity to preserve its shape and prevent shrinkage.
References in periodicals archive ?
Similarly to the successful starting steps (4) of more recent developments (6) on nonlinear creep of macromolecular materials, let us first briefly consider as paradigm of those elementary structural features and motions a set of interchanging "gauche" and "trans" chain conformers. In a hypothetically equilibrated material, their initial equilibrium would of course be reasonably described by Boltzmann's distribution at any given constant temperature, but in real (most often nonequilibrium) situations that will not be the case, depending on the exact initial state (e.g., degree of annealing and orientation) of the system.
In addition, when [H.sub.48] ([delta] = 4.45 ppm) is irradiated, we observe at [H.sub.58] a NOE ([zeta] = 34%) in the major conformer and a NOE ([zeta] = 10%) in the minor conformer (Figure 6).
Colorless oil, yield 110 mg (68%), [[alpha]].sub.D.sup.23] = +31.1 (c=1.5,CH[Cl.sub.3]); [1.sup]H NMR(500 MHz, CD[Cl.sub.3], E/Z and conformer mixture): [delta] = 7.42-7.27 (m, 10H, Ar-H), 7.02/6.91 (s, 1H, Ch), 6.07/[5.99.sub.trans], 5.72/[5.67.sub.cis] (2d, [J.sub.trans] = 15.7 Hz and 2d, [J.sub.cis] = 11.6 Hz, 1H, CH), 5.54-5.11 (m, 5H, Bn-[CH.sub.2],CH), 4.97 (m, 1H, CH), 2.45 (m, 1H, [CH.sub.2]), 2.31-2.03 (m, 4H, [CH.sub.2]), 1.96 (m, 1H, [CH.sub.2]), 1.05-0.95 (m, 3H, [CH.sub.3]).
In the absence of a known nucleic acid genome, it has been proposed that the strain-like properties of different TSE agents are encoded by distinct self-propagating conformational variants (conformers) of [PrP.sup.d] (3).
The "conformer" learner is described as preferring routine, explicit, supportive environments in which all expectations are made clear.
3, conformers of type 2 are by far statistically more valid at 300 K than conformer types 1 and 3 (note the result of MD run: see item 2 in Table 1), i.e.
Meme si aucune modification n'est apportee dans la loi, les societes alimentaires canadiennes etudient actuellement des moyens de se conformer aux restrictions sur les revendications des glucides, tout en communiquant aux consommateurs que les produits en contiennent peu.
La Commission estime que l'aide aura pour effet d'accelerer les projets de recherche vises par les aides et de leur permettre de se conformer au rythme de developpement de chaque generation de circuits integres telle qu'il est fixe par l'International Technology Roadmap for Semiconductors (ITRS).
"The free-volume and transition temperature theories, however, are less direct than the conformer approach and are losing support."