conformation

(redirected from conformationally)
Also found in: Dictionary, Thesaurus, Legal, Encyclopedia.

con·for·ma·tion

(kon'fōr-mā'shŭn),
The spatial arrangement of a molecule achieved by rotation of groups about single covalent bonds, without breaking any covalent bonds; the latter restriction differentiates conformation from configuration (as in anomers and related stereoisomers) where a bond or bonds must be broken in going from one form (configuration) to another. Conformation is one of the most important aspects of sugar chemistry and is basic to an understanding of the chemical properties of sugars. Compare: configuration.

con·for·ma·tion

(kon'fōr-mā'shŭn)
The spatial arrangement of a molecule achieved by rotation of groups about single covalent bonds, without breaking any covalent bonds.
Compare: configuration

conformation

(kŏn″for-mā′shŭn)
The form or shape of a part, body, material, or molecule.

conformation

symmetry, size and shape of the various body regions relative to each other or the general appearance of the animal in terms of satisfying the observer's appreciation of what is a desirable appearance. Most breed societies issue lists of desirable and undesirable points of conformation. Most of them are desirable. Some are not and react adversely on the animals' well-being. Desirable conformation may also be indicated by diagrams or photographs.
Also may refer to the spatial arrangement of atoms in a molecule.

mitochondrial conformation
mitochondria may be in an abnormal state of condensed conformation, detected by comparison with mitochondria of orthodox status; orthodox conformation is linked to inactive oxidase phosphorylation, condensed to active phosphorylation.
References in periodicals archive ?
Dipole moment of conformationally restricted chiral biphenyl dopant 1 containing methyl, carboxylate and nitro functional groups at positions2(2?
Inhibition and substrate activity of conformationally rigid vigabatrin analogues with [gamma]-aminobutyric acid aminotransferase.
It is likely that antibodies raised against the zymogen can have different reactivities toward proCPU, proCPU bound to plasminogen, CPU, and conformationally and proteolytically inactivated forms of proCPU and CPU (23, 24, 31).
The title compound is needed as a precursor in the synthesis of conformationally constrained analogues of the antimalarial compound mefloquine.
The compounds studied are selected from two main areas of our research; the study of hydrogen-bond networks and polymorphism, and consist of single and multi-component systems containing both rigid and conformationally flexible molecules.
Recently, boron functionalised vicinal dioxime complexes (gated glyoximes) have provided conformationally switchable metallocyclophane hosts in which non-bonded interactions (coulombic, charge transfer, H-bonding, dipolar forces) between the bound axial substrate and the macrocycle superstructure may be studied in detail.
Conformationally constrained tricyclic HIV integrase inhibitors
2013) The orientation of the terminal fBu group of antillatoxin is important for potent toxicity: design, synthesis and biological evaluation of conformationally restricted analogues of antillatoxin.
Drug discovery company Marina Biotech Inc (OTC Markets:MRNA) Friday reported the execution of a licensing agreement for its Conformationally Restricted Nucleotide (CRN) technology for the development of both single- and double-stranded oligonucleotide therapeutics.
But conformationally he was not good and only sold for 5,000gns as a foal," said Thorman.
The conformationally insensitive N-H stretching mode cannot be separated into crystalline and amorphous hydrogen-bonded phases [42].
2]M at physiologic pH and temperature is more conformationally unstable, i.