confocal microscopy


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Related to confocal microscopy: fluorescence microscopy

confocal microscopy

Microscopy that permits high-resolution analysis of serial optical sections (microscopic tomograms) into the depths of tissues or cells.
See also: microscopy

microscopy

examination with a microscope.
confocal microscopy
a technique for obtaining high resolution images and 3-D reconstructions of biological specimens; a laser light beam is expanded to make optimal use of the optics in the objective lens and is turned into a scanning beam via an x-y deflection mechanism and is focused to a small spot by the objective lens onto a fluorescent specimen. The mixture of reflected light and emitted fluorescent light is captured by the same objective and after conversion into a static beam by the x-y scanner device is focused onto a photodetector (photomultiplier) via a dichroic mirror (beam splitter) to create the final image. Called also laser scanning microscopy; confocal scanning laser microscopy.
immunoelectron microscopy
the mixing of antibody with an antigen such as a virus on a specimen grid so as to increase the probability of visualizing a virus and to identify (type) the kind of virus present in the specimen, or antibody may be conjugated with gold and used to visualize and determine the location of specific antigenic determinants on a specimen.
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Guitera P Pellacani G, Crotty KA, et al: The impact of in vivo reflectance confocal microscopy on the diagnostic accuracy of lentigo maligna and equivocal pigmented and nonpigmented macules of the face.
Reflectance confocal microscopy: its use in melanocyte lesions and morphology of normal skin/Reflektans konfokal mikroskopi; normal deri morfolojisi ve melanositik lezyonlarda kullanimi
When conjugated to antibodies that bind specifically to proteins present on the surface of cancer cells but not on normal cells, thousands or millions of nanoparticles will attach to a single cancerous cell, and this high density causes the cell membrane to appear many times brighter than normal cells when viewed using confocal microscopy.
Optical diagnostics for early detection of oral cancer
In this study, we aim to contribute to the elucidation of the arrangement of the placental microvascular bed by 3-D renderings of villous vessels, using confocal microscopy and tools of computer-based visualization.
3-D study of vessels in peripheral placental villi
We have shown, by use of confocal microscopy and transmission electron microscopy, internalization of Eu[P0.
Lanthanide phosphate nanorods as inorganic fluorescent labels in cell biology research
Further analysis of individual cells with confocal microscopy "showed that hundreds of marrow-derived cells in brain sections expressed gene products typical of neurons," they reported.
Adult bone marrow transfers capable of expressing nerve cell proteins
Excitation source for high contrast, deep imaging in confocal microscopy and flow cytometry
World's First Commercially Available 607nm Orange Laser from Lumany
1 confocal microscopy system to be assigned to soc 2 department of experimental oncology translational research cro of aviano.
No. 1 confocal microscopy system to be assigned to soc 2 department of experimental oncology translational research cro of aviano
It combines two separate technologies -- confocal microscopy and fluorescence lifetime imaging -- to noninvasively evaluate both the structural changes of tissue as well as molecular changes that take place on a cellular and tissue level.
Noninvasive Detection, Diagnosis of Oral Cancer
Confocal microscopy was first described in the 1950s by Minsky (5) and is now a relatively mature technology with many commercial implementations.
Advances in microscopy techniques
His new computer model takes slices of laser confocal microscopy images of cells and reconstructs a whole, virtual version of an individual cell, allowing researchers to evaluate how that cell will respond to different mechanical stimuli.
How fat cells respond to mechanical stress
Other topics include low-shrinkage composites, simultaneous fluorescence and reflection confocal microscopy of living cell interactions, the fracture resistance of non-metal posts, and an assessment of genetic damage and cellular death.
Dental materials research
The confocal microscopy segment is the smallest of the surface science techniques (IBO's surface science category excludes confocal systems that are dedicated units for microarray scanning and other purposes).
Surface science: focusing on bioanalysis

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