confocal


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con·fo·cal mi·cro·scope

a microscope that allows the observer to visualize objects in a single plane of focus, thereby creating a sharper image (usually the objects are fluorescent molecules); a refinement of this microscope uses optic sectioning and a computer to record serial sections. This permits three-dimensional reconstruction.

confocal 

Having the same focus. Example: in a slit-lamp, the microscope and the illumination system have the same focus, i.e. they are confocal. See confocal microscope; confocal scanning laser ophthalmoscope.

confocal

see confocal microscopy.
References in periodicals archive ?
Despite the fact that the "gold standard" for the pathomorphological evaluation of normal and affected skin in dermatology is still biopsy followed by histological study, according to the Russian researchers, "there is always a demand in the applied medicine field for informative, high-tech and non-invasive diagnostic methods, which include confocal laser scanning microscopy," they stated.
In addition to performing standard fixed preparation and live-cell confocal imaging, Vutara 352 with the Opterra SRoption enables correlative imaging to provide live, high-resolution imaging for sample investigation prior to super-resolution imaging, as well as the capability to combine super-resolution images with confocal images for contextual information.
EIDON's white-light, confocal imaging technology facilitates diagnosis and management of retinal disease.
To overcome this limitation, Maitland paired the technology with another technology known as confocal microscopy.
Initially designed in 2004, endoscope-based CLE (eCLE; Pentax Corporation, Montvale, New Jersey) uses a fiber-optic cable to convey blue laser light to a miniaturized confocal microscope integrated into the 12-mm-diameter tip of an endoscope.
Confocal laser endomicroscopy allows a clinician to look at living tissue in an area of interest, as if the tissue were under a microscope, while the endoscope is still in the patient.
The Olympus FluoView FV300 cLSM offers two confocal fluorescence detection channels and a third transmitted light detection channel, making it a highly flexible entry-level confocal system for all applications.
To reject the out-of-focus light, the microscope places a spinning disk, with an alternating pattern of vertical and horizontal slits, in the confocal plane of the microscope.
Siscan MC64 sensor is a confocal displacement sensor with vertically oscillating turning fork for accurate and fast 3D surface scanning at great speed.
WASHINGTON -- Corneal confocal microscopy provides a means for noninvasively diagnosing neuropathy early on in diabetic patients and for following the course of the disease during treatment, several speakers said at the annual scientific sessions of the American Diabetes Association.