cone biopsy

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Related to cone biopsies: conization, Cervical conization

biopsy

 [bi´op-se]
removal and examination, usually microscopic, of tissue from the living body, often to determine whether a tumor is malignant or benign; biopsies are also done for diagnosis of disease processes such as infections.
Technique for endometrial biopsy. Longitudinal strips of the endometrium are sampled using an in-and-out and rotational motion. From Rakel, 2000.
aspiration biopsy one in which tissue is obtained by application of suction through a needle attached to a syringe.
brush biopsy one in which the sample is obtained by a brush with stiff bristles introduced through an endoscope, such as for a tissue sample from an inaccessible place such as the renal pelvis or bronchus.
chorionic villus biopsy chorionic villus sampling.
cone biopsy one in which an inverted cone of tissue is excised, as from the uterine cervix.
endoscopic biopsy removal of tissue by instruments inserted through an endoscope.
excisional biopsy removal of biopsy tissue by surgical cutting, such as a lumpectomy.
fine-needle aspiration biopsy aspiration biopsy using a fine needle. For superficial tissue such as the thyroid, breast, or prostate the needle is unguided, but for deep tissue it must be guided radiologically.
incisional biopsy biopsy of a selected portion of a lesion.
needle biopsy (percutaneous biopsy) one in which tissue is obtained by insertion through the skin of a special type of needle (see biopsy needle).
punch biopsy one in which tissue is obtained by a punch-type instrument.
sentinel node biopsy biopsy of a sentinel node (the first lymph node to receive lymphatic drainage from a malignant tumor). It is identified as follows: a dye and a radioactive substance are injected into the body, which causes certain nodes to “light up” like a sentinel, indicating that they are the most appropriate ones for examination. They are detected by both the light created by the dye and the radioactive substance that is monitored by a gamma camera. If the sentinel nodes do not contain malignant cells, this usually eliminates the need for removal of more distal nodes. Called also intraoperative lymphatic mapping.
shave biopsy biopsy of a skin lesion by excising it with a cut parallel to the surface of the surrounding skin.
stereotactic biopsy biopsy of the brain using a stereotactic technique to locate the biopsy site. This can be done as a minimally invasive surgery technique. The patient's head is held in a special rigid frame so that a probe can be directed into the brain through a small hole in the skull.
sternal biopsy biopsy of bone marrow of the sternum removed by puncture or trephining; see also sternal puncture.

cone biopsy

Conization The surgical excision of the cone-shaped uterine cervix, which encompasses the ectocervix and endocervical portion of the uterine cervix; it is performed as definitive therapy for CIN 1 to 3, and has been used for circumscribed carcinoma in situ, microinvasive SCC, and rarely, condylomas, confined to the cervix, while preserving the uterus Complications Bleeding, infection, cervical stenosis, cervical incompetence. See Cervix, CIN, HPV, HSIL, LSIL. Cf LEEP.

cone biopsy

The removal of a cone-shaped segment of tissue from the inside of the neck of the womb to provide material for positive microscopic diagnosis. This is done under general anaesthesia when a cervical smear test suggests that cancer may be present.
References in periodicals archive ?
For example, half the referrals by Pfenninger were for cold cone biopsies. In contrast, many LEEP procedures performed in the Cervical Dysplasia Clinic were LEEP cones.
Negative cone biopsies: a reappraisal [erratum in J Reprod Med.
The significance of positive margins in loop electrosurgical cone biopsies. Obstet Gynecol.
In this cohort, a total of 5,019 Pap smears, 33 colposcopies, 72 biopsies, 7 loop electrosurgical excision procedures, 2 cone biopsies, and 4 D&Cs were performed to identify one woman with a cervical biopsy read as "mild to moderate dysplasia." This finding prompted our recommendation.
Two hundred and twelve women had a cytologic follow-up, with at least 1 Papanicolaou smear, and 193 women underwent biopsy (punch biopsies or cone biopsies).
Studies have shown that cone biopsies for AIS with negative margins result in residual disease in a hysterectomy 6% to 44% of the time, whereas cone biopsies for AIS with positive margins are associated with residual disease 44% to 75% of the time.
In pathology reports for LEEPs and cone biopsies, the size of the invasive tumor, including depth of stromal invasion and horizontal tumor spread, should always be included, as well as the presence of lymphovascular invasion (LVI) and margin status.