conditional lethal

conditional lethal

a genetic MUTATION that causes death in certain circumstances (e.g. high temperature) but not in others (e.g. low temperature).
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005
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In designing such experiments, it is most straightforward to use microorganisms, given their short generation time and readily available conditional lethal mutations.
Finally, it should be noted that the use of conditional lethals, while allowing observation of a microevolutionary change within a manageable period, may also unintentionally create or reinforce a belief that selection primarily occurs in gross mutants and in short time frames.
When a fly has to fly to reproduce: selection against conditional recessive lethals in Drosophila
The compositions are DNA constructs that comprise novel arrangements of T-DNA molecules containing genes of interest, positive selectable marker genes, and conditional lethal genes.
Monsanto obtains United States patent

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