Caption: Figure 3: Representative concentric hypertrophy
protein products extracted from the left ventricles of study rats in each group, control rats; IA, induced aging rats; AL, AOF low; AM, AOF medium; AH, AOF high, were measured using Western blotting.
(a) Parasternal long axis view (a) showed severe concentric hypertrophy
of interventricular septum (IVS) and LV free wall, but without an echogenic mass in the apex.
Many studies have found concentric hypertrophy
in the hearts of trained rats and mice, although their training protocols are controversial.
Hypertensive Response to Exercise And the Left Ventricle HNTRE No HTNRE Number of patients 136 270 left ventricular measurement Mass (mean) 199 g 184g Mass index (mean) 96 g/[m.sup.2] 103 g/[m,sup.2] Concentric hypertrophy
(prevalence) 25% 16% Eccentric hypertrophy (prevalence) 12% 7.4% Note: HTNRE = hypertensive response to exercise Source: Dr.
Long-standing hypertension triggers concentric hypertrophy
and increases LV passive stiffness, which leads to impaired LV diastolic function and then to the development of decompensated heart failure.
The overload of pressure can result in arterial hypertension, arteriosclerosis and, occasionally, aortic stenosis, causing LV concentric hypertrophy
(increase in mass secondary to increase in myocyte thickness, without significant alteration in ventricular volume and relative thickness).
Long-term hypertension is an influence on ventricular hypertrophy development, specifically concentric hypertrophy
(Verdecchia et al.
Transthoracic and transesophageal echocardiography revealed massive concentric hypertrophy
This remodeling finally results in the concentric hypertrophy
of LV, i.e.
In clinical understanding, the term "structural remodeling" refers usually to changes in the LVH shape in terms of eccentric and concentric hypertrophy
. However, the changed shape of the left ventricle is conditioned by underlying changes at tissue, cellular and subcellular levels and these changes have been reported already in early stages of hypertension and LVH, both in animal models and in humans (21, 22).
The left and right ventricles appeared to have concentric hypertrophy
with multiple, prominent myocardial trabeculations and deep intertrabecular recesses communicating with the main ventricular cavity (Fig.