concanavalin


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concanavalin

 [kon″kah-nav´ah-lin]
a lectin isolated from the jack bean (Canavalia ensiformis) that agglutinates mammalian erythrocytes and is a mitogen that stimulates predominantly T lymphocytes. Abbreviated ConA.
References in periodicals archive ?
Lactose hydrolysis from milk/whey in batch and continuous processes by concanavalin A-Celite 545 immobilized Aspergillus oryzae [beta]-galactosidase.
A concanavalin A-like lectin domain in the CHS1/LYST protein, shared by members of the BEACH family.
Wendel, "A T cell-dependent experimental liver injury in mice inducible by concanavalin A," The Journal of Clinical Investigation, vol.
Zhang et al., "Pretreatment with propylene glycol alginate sodium sulfate ameliorated concanavalin A-induced liver injury by regulating the PI3K/Akt pathway in mice," Life Sciences, vol.
Concanavalin A was added at 1 [micro]g/ml and T cell proliferation was measured 72 h later.
Sass et al., "TNF-[alpha]-induced expression of adhesion molecules in the liver is under the control of TNFR1--relevance for concanavalin A-induced hepatitis," Journal of Immunology, vol.
On day 35, splenocytes isolated from the vaccinated mice were restimulated with concanavalin A, no peptide, an irrelevant [beta]-galactosidase peptide, or pools of overlapping peptides spanning the VEEV IAB strain Trinidad donkey E2 or E1 envelope glycoproteins and analyzed by IFN-[gamma] ELISpot.
Phytohemagglutinin (used at doses of 5 [micro]g/mL) and concanavalin A (used at doses of 5 [micro]g/mL) were purchased from Sigma-Aldrich (St.
To examine the role of KCs in local acute inflammation, we investigated T cell-mediated acute hepatitis model induced by concanavalin A (ConA).
As a prototype drug of mTOR pathway inhibitors, Rapamycin (RAPA) effectively treated liver injury induced by concanavalin A (Con A), realizing that RAPA reduced transaminase levels and suppressed proinflammatory cytokines IFNgamma and TNF-alpha production [66].
Dent et al., "Short-form Ron receptor is required for normal IFN-[gamma] production in concanavalin A-induced acute liver injury," American Journal of Physiology--Gastrointestinal and Liver Physiology, vol.